Diffusion MRI has provided the neuroimaging community with a powerful tool to acquire in-
vivo data sensitive to microstructural features of white matter, up to 3 orders of magnitude …

Multi-tissue constrained spherical deconvolution of diffusion MRI data yields white matter
fibre orientation distributions, from which a quantitative metric of apparent fibre density can …

White matter (WM) fiber bundles change dynamically with age. These changes could be
driven by alterations in axonal diameter, axonal density, and myelin content. In this study, we …

The neuronal differences contributing to the etiology of autism spectrum disorder (ASD) are
still not well defined. Previous studies have suggested that myelin and axons are disrupted …

Our study explores the potential of conventional and advanced diffusion MRI techniques
including diffusion tensor imaging (DTI), and single-shell 3-tissue constrained spherical …

White matter hyperintensities (WMH) are regions of high signal intensity typically identified
on fluid attenuated inversion recovery (FLAIR). Although commonly observed in elderly …

Functional connectivity between the amygdala and the medial prefrontal cortex (mPFC) has
been identified as a neural substrate of emotion regulation that undergoes changes …

Multi-tissue constrained spherical deconvolution (MT-CSD) leverages the characteristic b-
value dependency of each tissue type to estimate both the apparent tissue densities and the …

Individuals with Mild Cognitive Impairment (MCI) are at an elevated risk of dementia and
exhibit deficits in cognition and cortical gray matter (GM) volume, thickness, and …

Puberty is a key event in adolescent development that involves significant, hormone-driven
changes to many aspects of physiology including the brain. Understanding how the brain …