Hepatic inflammatory responses in liver fibrosis
L Hammerich, F Tacke - Nature Reviews Gastroenterology & …, 2023 - nature.com
Chronic liver diseases such as nonalcoholic fatty liver disease (NAFLD) or viral hepatitis are
characterized by persistent inflammation and subsequent liver fibrosis. Liver fibrosis critically …
characterized by persistent inflammation and subsequent liver fibrosis. Liver fibrosis critically …
Fibrosis: from mechanisms to medicines
NC Henderson, F Rieder, TA Wynn - Nature, 2020 - nature.com
Fibrosis can affect any organ and is responsible for up to 45% of all deaths in the
industrialized world. It has long been thought to be relentlessly progressive and irreversible …
industrialized world. It has long been thought to be relentlessly progressive and irreversible …
Molecular and cellular mechanisms of liver fibrosis and its regression
T Kisseleva, D Brenner - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Chronic liver injury leads to liver inflammation and fibrosis, through which activated
myofibroblasts in the liver secrete extracellular matrix proteins that generate the fibrous scar …
myofibroblasts in the liver secrete extracellular matrix proteins that generate the fibrous scar …
Crosstalk between oxidative stress and inflammatory liver injury in the pathogenesis of alcoholic liver disease
Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
Liver inflammation and fibrosis
Y Koyama, DA Brenner - The Journal of clinical …, 2017 - Am Soc Clin Investig
Chronic liver inflammation leads to fibrosis and cirrhosis, which is the 12th leading cause of
death in the United States. Hepatocyte steatosis is a component of metabolic syndrome and …
death in the United States. Hepatocyte steatosis is a component of metabolic syndrome and …
[HTML][HTML] Critical role of interleukin (IL)-17 in inflammatory and immune disorders: An updated review of the evidence focusing in controversies
Abstract Interleukin 17 (IL-17) is a proinflammatory cytokine that has been the focus of
intensive research because of its crucial role in the pathogenesis of different diseases …
intensive research because of its crucial role in the pathogenesis of different diseases …
Inflammatory pathways in alcoholic steatohepatitis
Inflammatory processes are primary contributors to the development and progression of
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …
[HTML][HTML] Cirrhosis-associated immune dysfunction: distinctive features and clinical relevance
A Albillos, M Lario, M Álvarez-Mon - Journal of hepatology, 2014 - Elsevier
The term cirrhosis-associated immune dysfunction refers to the main syndromic
abnormalities of immune function, immunodeficiency and systemic inflammation that are …
abnormalities of immune function, immunodeficiency and systemic inflammation that are …
[HTML][HTML] Pathogenesis of alcoholic liver disease: role of oxidative metabolism
E Ceni, T Mello, A Galli - World Journal of Gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Alcohol consumption is a predominant etiological factor in the pathogenesis of chronic liver
diseases, resulting in fatty liver, alcoholic hepatitis, fibrosis/cirrhosis, and hepatocellular …
diseases, resulting in fatty liver, alcoholic hepatitis, fibrosis/cirrhosis, and hepatocellular …
Alcoholic liver disease: pathogenesis and new therapeutic targets
B Gao, R Bataller - Gastroenterology, 2011 - Elsevier
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide and can
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …