Malaria parasite development in the mosquito and infection of the mammalian host
ASI Aly, AM Vaughan, SHI Kappe - Annual review of …, 2009 - annualreviews.org
Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …
[HTML][HTML] Looking under the skin: the first steps in malarial infection and immunity
Malaria, which is caused by Plasmodium spp., starts with an asymptomatic phase, during
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …
Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression
E Lasonder, SR Rijpma, BCL van Schaijk… - Nucleic acids …, 2016 - academic.oup.com
Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and
subsequent gamete fertilization in mosquitoes is essential for the spreading of the disease …
subsequent gamete fertilization in mosquitoes is essential for the spreading of the disease …
Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum
The malaria parasite Plasmodium falciparum has a great capacity for evolutionary
adaptation to evade host immunity and develop drug resistance. Current understanding of …
adaptation to evade host immunity and develop drug resistance. Current understanding of …
[HTML][HTML] Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites
Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must
navigate the host skin and vasculature to infect the liver. This journey requires distinct …
navigate the host skin and vasculature to infect the liver. This journey requires distinct …
[HTML][HTML] Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance
Erythrocytes carrying a variant hemoglobin allele (HbS), which causes sickle cell disease
and resists infection by the malaria parasite Plasmodium falciparum. The molecular basis of …
and resists infection by the malaria parasite Plasmodium falciparum. The molecular basis of …
[HTML][HTML] Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass …
Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly
motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to …
motile invasive cell that targets hepatocytes in the liver for infection. A promising approach to …
[HTML][HTML] Protein export marks the early phase of gametocytogenesis of the human malaria parasite Plasmodium falciparum
Despite over a century of study of malaria parasites, parts of the Plasmodium falciparum life
cycle remain virtually unknown. One of these is the early gametocyte stage, a round shaped …
cycle remain virtually unknown. One of these is the early gametocyte stage, a round shaped …
[HTML][HTML] Universal Features of Post-Transcriptional Gene Regulation Are Critical for Plasmodium Zygote Development
A universal feature of metazoan sexual development is the generation of oocyte P granules
that withhold certain mRNA species from translation to provide coding potential for proteins …
that withhold certain mRNA species from translation to provide coding potential for proteins …
[HTML][HTML] Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging
IHJ Ploemen, M Prudêncio, BG Douradinha… - PloS one, 2009 - journals.plos.org
The quantitative analysis of Plasmodium development in the liver in laboratory animals in
cultured cells is hampered by low parasite infection rates and the complicated methods …
cultured cells is hampered by low parasite infection rates and the complicated methods …