[HTML][HTML] Oxidative stress in cancer
Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution
in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting …
in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting …
[HTML][HTML] Nutritional components in Western diet versus Mediterranean diet at the gut microbiota–immune system interplay. Implications for health and disease
C García-Montero, O Fraile-Martínez… - Nutrients, 2021 - mdpi.com
The most prevalent diseases of our time, non-communicable diseases (NCDs)(including
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …
[HTML][HTML] Metabolism and colorectal cancer
Reprogrammed metabolism is a hallmark of colorectal cancer (CRC). CRC cells are geared
toward rapid proliferation, requiring nutrients and the removal of cellular waste in nutrient …
toward rapid proliferation, requiring nutrients and the removal of cellular waste in nutrient …
[HTML][HTML] Oxidative cell death in cancer: mechanisms and therapeutic opportunities
Reactive oxygen species (ROS) are highly reactive oxygen-containing molecules generated
as natural byproducts during cellular processes, including metabolism. Under normal …
as natural byproducts during cellular processes, including metabolism. Under normal …
[HTML][HTML] High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer
F Böttger, A Vallés-Martí, L Cahn… - Journal of experimental & …, 2021 - Springer
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer
agent when administered intravenously and in high doses (high-dose IVC). Early phase …
agent when administered intravenously and in high doses (high-dose IVC). Early phase …
[HTML][HTML] Cancer immunotherapy with γδ T cells: many paths ahead of us
D Kabelitz, R Serrano, L Kouakanou, C Peters… - Cellular & molecular …, 2020 - nature.com
Abstract γδ T cells play uniquely important roles in stress surveillance and immunity for
infections and carcinogenesis. Human γδ T cells recognize and kill transformed cells …
infections and carcinogenesis. Human γδ T cells recognize and kill transformed cells …
[HTML][HTML] Targeting EMT in cancer with repurposed metabolic inhibitors
Epithelial-to-mesenchymal transition (EMT) determines the most lethal features of cancer,
metastasis formation and chemoresistance, and therefore represents an attractive target in …
metastasis formation and chemoresistance, and therefore represents an attractive target in …
Smartphone light-driven zinc porphyrinic MOF nanosheets-based enzyme-free wearable photoelectrochemical sensor for continuous sweat vitamin C detection
Maintaining normal vitamin C levels is essential for the proper functioning of the body's
immune system. The development of real-time non-invasive wearable sensors for …
immune system. The development of real-time non-invasive wearable sensors for …
Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome
The recent outbreak of Covid19 has required urgent treatments for numerous patients. No
suitable vaccines or antivirals are available for Covid19. The efficiency against Covid19 of …
suitable vaccines or antivirals are available for Covid19. The efficiency against Covid19 of …
Vitamin C enhances NF-κB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells
O Morante-Palacios, G Godoy-Tena… - Nucleic acids …, 2022 - academic.oup.com
Dendritic cells (DCs), the most potent antigen-presenting cells, are necessary for effective
activation of naïve T cells. DCs' immunological properties are modulated in response to …
activation of naïve T cells. DCs' immunological properties are modulated in response to …