Among the many neuromodulators used by the mammalian brain to regulate circuit function
and plasticity, dopamine (DA) stands out as one of the most behaviorally powerful …

Psychostimulants such as cocaine have been used as performance enhancers throughout
recorded history. Although psychostimulants are commonly prescribed to improve attention …

The cerebellum, a primary brain structure involved in the control of sensorimotor tasks, also
contributes to higher cognitive functions including reward, emotion and social interaction …

Dopamine is an important neuromodulator that exerts widespread effects on the central
nervous system (CNS) function. Disruption in dopaminergic neurotransmission can have …

Cortical neuromodulatory transmitter systems refer to those classical neurotransmitters such
as acetylcholine and monoamines, which share a number of common features. For instance …

Substantial evidence indicates that the lateral septum (LS) plays a critical role in regulating
processes related to mood and motivation. This review presents findings from the basic …

Among the neuromodulators that regulate prefrontal cortical circuit function, the
catecholamine transmitters norepinephrine (NE) and dopamine (DA) stand out as powerful …

The basal ganglia are a highly interconnected set of subcortical nuclei and major atrophy in
one or more regions may have major effects on other regions of the brain. Therefore, the …

Dopamine is an important neurotransmitter involved in motor control, endocrine function,
reward, cognition and emotion. Dopamine receptors belong to the superfamily of G protein …

The mechanism of action of the combination therapy, naltrexone/bupropion (NB), for obesity
has not been fully described to date. Weight loss attempts rarely result in long-term success …