Formulation and characterization of liposomes containing drug absorption enhancers for optimized anti-HIV and antimalarial drug delivery
PS Kheoane, GMA Enslin, C Tarirai - Drug Delivery and Translational …, 2023 - Springer
Most of the current clinically used anti-HIV and antimalarial drugs have low bioavailability,
either due to poor solubility and permeability, rapid clearance from anatomical reservoirs …
either due to poor solubility and permeability, rapid clearance from anatomical reservoirs …
[HTML][HTML] Can rooibos (Aspalathus linearis) tea have an effect on conventional antimicrobial therapies?
Z Hübsch, SF Van Vuuren, RL Van Zyl - South African Journal of Botany, 2014 - Elsevier
One of the most commonly consumed and commercially relevant herbal teas in South Africa
is rooibos tea, prepared from the plant, Aspalathus linearis (Burm. F.) Dahlg. In orthodox …
is rooibos tea, prepared from the plant, Aspalathus linearis (Burm. F.) Dahlg. In orthodox …
Lipid-lowering effect and oral transport characteristics study of curculigoside
A Wang, J Ning, L Zhao, R Xu - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Introduction The incidence of metabolic disorders during pregnancy is increasing year by
year, with diseases including hypertension and hyperlipidemia. Statins are the primary …
year, with diseases including hypertension and hyperlipidemia. Statins are the primary …
Transepithelial transport of PAMAM dendrimers across isolated rat jejunal mucosae in ussing chambers
D Hubbard, H Ghandehari, DJ Brayden - Biomacromolecules, 2014 - ACS Publications
Oral delivery remains a challenge for poorly permeable hydrophilic macromolecules. Poly
(amido amine)(PAMAM) dendrimers have shown potential for their possible oral delivery …
(amido amine)(PAMAM) dendrimers have shown potential for their possible oral delivery …
Regional morphology and transport of PAMAM dendrimers across isolated rat intestinal tissue
D Hubbard, T Bond… - Macromolecular …, 2015 - Wiley Online Library
Intestinal permeability of PAMAM dendrimers has been observed, giving rationale for their
use in oral drug delivery as potential carriers of associated molecules. This study assessed …
use in oral drug delivery as potential carriers of associated molecules. This study assessed …
[PDF][PDF] Antioxidant and prebiotic activity of selected edible wild plant extracts
Edible wild plants were investigated as potential sources of antioxidants and prebiotics to
benefit human health. Antioxidant activity, ascorbic acid and total dietary fibre contents were …
benefit human health. Antioxidant activity, ascorbic acid and total dietary fibre contents were …
Determination of effective concentrations of drug absorption enhancers using in vitro and ex vivo models
PS Kheoane, GMA Enslin, C Tarirai - European Journal of Pharmaceutical …, 2021 - Elsevier
Background Achievement of an effective concentration of the pharmaceutically active
ingredient in the blood and/or at the target site is an important aspect in the formulation of …
ingredient in the blood and/or at the target site is an important aspect in the formulation of …
Absorptive and secretory transport of selected artemisinin derivatives across Caco-2 cell monolayers
Background: Malaria continues to be a major health concern and affects more than 200
million people a year. Drugs currently used for treatment of malaria are increasingly …
million people a year. Drugs currently used for treatment of malaria are increasingly …
Harnessing herb-drug interactions for enhanced oral delivery of anti-HIV and antimalarial drugs using colloidal formulations
PS Kheoane - 2020 - repository.tml.nul.ls
Problem: Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS)
and malaria infect and kill a large population globally. Most of the current clinically used anti …
and malaria infect and kill a large population globally. Most of the current clinically used anti …