[HTML][HTML] MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer

G Bertoli, C Cava, I Castiglioni - Theranostics, 2015 - ncbi.nlm.nih.gov
Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of
several human cancers, including breast cancer (BC), as strong evidence has been found …

Bioinformatic tools for microRNA dissection

MM Akhtar, L Micolucci, MS Islam, F Olivieri… - Nucleic acids …, 2016 - academic.oup.com
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …

[HTML][HTML] MicroRNAs as clinical tools for diagnosis, prognosis, and therapy in prostate cancer

F Ghamlouche, A Yehya, Y Zeid, H Fakhereddine… - Translational …, 2023 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed cancers among men
worldwide. Despite the presence of accumulated clinical strategies for PCa management …

MatureBayes: A Probabilistic Algorithm for Identifying the Mature miRNA within Novel Precursors

K Gkirtzou, I Tsamardinos, P Tsakalides, P Poirazi - PloS one, 2010 - journals.plos.org
Background MicroRNAs (miRNAs) are small, single stranded RNAs with a key role in post-
transcriptional regulation of thousands of genes across numerous species. While several …

A review of computational tools in microRNA discovery

CPC Gomes, JH Cho, L Hood, OL Franco… - Frontiers in …, 2013 - frontiersin.org
Since microRNAs (miRNAs) were discovered, their impact on regulating various biological
activities has been a surprising and exciting field. Knowing the entire repertoire of these …

Discovery of novel microRNAs in female reproductive tract using next generation sequencing

CJ Creighton, AL Benham, H Zhu, MF Khan, JG Reid… - PloS one, 2010 - journals.plos.org
MicroRNAs (miRNAs) are small non-coding RNAs that mediate post-transcriptional gene
silencing. Over 700 human miRNAs have currently been identified, many of which are …

Computational prediction of the localization of microRNAs within their pre-miRNA

M Leclercq, AB Diallo, M Blanchette - Nucleic acids research, 2013 - academic.oup.com
MicroRNAs (miRNAs) are short RNA species derived from hairpin-forming miRNA
precursors (pre-miRNA) and acting as key posttranscriptional regulators. Most …

miR-187 Is an Independent Prognostic Factor in Breast Cancer and Confers Increased Invasive Potential In Vitro

L Mulrane, SF Madden, DJ Brennan, G Gremel… - Clinical cancer …, 2012 - AACR
Purpose: Here, we describe an integrated bioinformatics, functional analysis, and
translational pathology approach to identify novel miRNAs involved in breast cancer …

Theranostic interpolation of genomic instability in breast cancer

R Rasool, I Ullah, B Mubeen, S Alshehri… - International Journal of …, 2022 - mdpi.com
Breast cancer is a diverse disease caused by mutations in multiple genes accompanying
epigenetic aberrations of hazardous genes and protein pathways, which distress tumor …

Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

C Cava, G Bertoli, I Castiglioni - BMC systems biology, 2015 - Springer
Background Development of human cancer can proceed through the accumulation of
different genetic changes affecting the structure and function of the genome. Combined …