Microphysiological systems (MPS) designed to study the complexities of the peripheral and
central nervous systems have made marked improvements over the years and have allowed …

A bioengineered spinal cord is fabricated via extrusion‐based multimaterial 3D bioprinting,
in which clusters of induced pluripotent stem cell (iPSC)‐derived spinal neuronal progenitor …

Spinal cord injury (SCI) is associated with currently irreversible consequences in several
functional components of the central nervous system. Despite the severity of injury, there …

Spinal cord injury can attenuate both motor and sensory function with minimal potential for
full recovery. Research utilizing human induced pluripotent stem cell (hiPSC)-derived spinal …

Numerous interventions have been explored in animal models using cells differentiated from
human induced pluripotent stem cells (iPSCs) in the context of neural injury with some …

Chronic spinal cord injury (SCI) is a devastating medical condition. In the acute phase after
injury, there is cell loss resulting in chronic axonal damage and loss of sensory and motor …

Differentiation of human pluripotent stem cells (hPSCs) into ectoderm provides neurons and
glia useful for research, disease modeling, drug discovery, and potential cell therapies. In …

Patients with chronic hypoxia show a higher tumor incidence; however, no primary common
cause has been recognized. Given the similarities between cellular reprogramming and …

Background There are currently no effective clinical therapies to ameliorate the loss of
function that occurs after spinal cord injury. Electrical stimulation of the rat spinal cord …

Abstract Mesenchymal Stem Cells (MSCs) derived from the embryonic mesoderm persist as
a viable source of multipotent cells in adults and have a crucial role in tissue repair. One of …