Prebiotic peptides: Molecular hubs in the origin of life

M Frenkel-Pinter, M Samanta, G Ashkenasy… - Chemical …, 2020 - ACS Publications
The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …

Systems chemistry

G Ashkenasy, TM Hermans, S Otto… - Chemical Society …, 2017 - pubs.rsc.org
Building on our ability to design and synthesise molecules and our understanding of the
noncovalent interactions between these molecules, the chemical sciences are currently …

Supramolecular polymers in aqueous media

E Krieg, MMC Bastings, P Besenius… - Chemical …, 2016 - ACS Publications
This review discusses one-dimensional supramolecular polymers that form in aqueous
media. First, naturally occurring supramolecular polymers are described, in particular …

Supramolecular systems chemistry

E Mattia, S Otto - Nature nanotechnology, 2015 - nature.com
The field of supramolecular chemistry focuses on the non-covalent interactions between
molecules that give rise to molecular recognition and self-assembly processes. Since most …

[HTML][HTML] From cascaded catalytic nucleic acids to enzyme–DNA nanostructures: controlling reactivity, sensing, logic operations, and assembly of complex structures

F Wang, CH Lu, I Willner - Chemical reviews, 2014 - ACS Publications
DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …

Catalytic peptide assemblies

O Zozulia, MA Dolan, IV Korendovych - Chemical Society Reviews, 2018 - pubs.rsc.org
Self-assembly of molecules often results in new emerging properties. Even very short
peptides can self-assemble into structures with a variety of physical and structural …

From self-replication to replicator systems en route to de novo life

P Adamski, M Eleveld, A Sood, Á Kun… - Nature Reviews …, 2020 - nature.com
The process by which chemistry can give rise to biology remains one of the biggest
mysteries in contemporary science. The de novo synthesis and origin of life both require the …

Mechanisms of autocatalysis

AJ Bissette, SP Fletcher - Angewandte Chemie International …, 2013 - Wiley Online Library
Self‐replication is a fundamental concept. The idea of an entity that can repeatedly create
more of itself has captured the imagination of many thinkers from von Neumann to …

An approach to the de novo synthesis of life

S Otto - Accounts of chemical research, 2021 - ACS Publications
Conspectus As the remit of chemistry expands beyond molecules to systems, new synthetic
targets appear on the horizon. Among these, life represents perhaps the ultimate synthetic …

Peptide nanofibers with dynamic instability through nonequilibrium biocatalytic assembly

S Debnath, S Roy, RV Ulijn - Journal of the American Chemical …, 2013 - ACS Publications
We demonstrate the formation of supramolecular peptide nanofibers that display dynamic
instability; ie, they are formed by competing assembly and disassembly reactions, where …