Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome
E Stener-Victorin, V Padmanabhan… - Endocrine …, 2020 - academic.oup.com
More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …
Polycystic ovarian syndrome: correlation between hyperandrogenism, insulin resistance and obesity
X Zeng, Y Xie, Y Liu, S Long, Z Mo - Clinica chimica acta, 2020 - Elsevier
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease
characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic …
characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic …
Melatonin ameliorates excessive PINK1/Parkin-mediated mitophagy by enhancing SIRT1 expression in granulosa cells of PCOS
S Yi, B Zheng, Y Zhu, Y Cai, H Sun… - American Journal of …, 2020 - journals.physiology.org
Mitochondrial injury in granulosa cells is associated with the pathogenesis of polycystic
ovary syndrome (PCOS). However, the protective effects of melatonin against mitochondrial …
ovary syndrome (PCOS). However, the protective effects of melatonin against mitochondrial …
The mechanism of androgen actions in PCOS etiology
V Rodriguez Paris, MJ Bertoldo - Medical sciences, 2019 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive-
age women. By comprising reproductive, endocrine, metabolic and psychological features …
age women. By comprising reproductive, endocrine, metabolic and psychological features …
Recent advances in emerging PCOS therapies
KA Glendining, RE Campbell - Current Opinion in Pharmacology, 2023 - Elsevier
Polycystic ovary syndrome is a prevalent endocrinopathy involving androgen excess, and
anovulatory infertility. The disorder is also associated with many comorbidities such as …
anovulatory infertility. The disorder is also associated with many comorbidities such as …
Defining the impact of dietary macronutrient balance on PCOS traits
Lifestyle, mainly dietary, interventions are first-line treatment for women with polycystic ovary
syndrome (PCOS), but the optimal diet remains undefined. We combined a …
syndrome (PCOS), but the optimal diet remains undefined. We combined a …
Androgens and ovarian function: translation from basic discovery research to clinical impact
In the last decade it has been revealed that androgens play a direct and important role in
regulating female reproductive function. Androgens mediate their actions via the androgen …
regulating female reproductive function. Androgens mediate their actions via the androgen …
The molecular mechanism of miR-96-5p in the pathogenesis and treatment of polycystic ovary syndrome
Y Liu, S Zhang, L Chen, X Huang, M Wang… - Translational …, 2023 - Elsevier
Polycystic ovary syndrome (PCOS), characterized by the androgen excess and arrest of
antral follicles, is a common endocrine disorder among women lacking specific diagnostic …
antral follicles, is a common endocrine disorder among women lacking specific diagnostic …
Notch signaling induced by endoplasmic reticulum stress regulates cumulus-oocyte complex expansion in polycystic ovary syndrome
H Koike, M Harada, A Kusamoto, C Kunitomi, Z Xu… - Biomolecules, 2022 - mdpi.com
Endoplasmic reticulum (ER) stress activated in granulosa cells contributes to the
pathophysiology of polycystic ovary syndrome (PCOS). In addition, recent studies have …
pathophysiology of polycystic ovary syndrome (PCOS). In addition, recent studies have …
Polycystic ovarian syndrome and fertility
JA Lentscher, B Slocum… - Clinical obstetrics and …, 2021 - journals.lww.com
Polycystic ovary syndrome (PCOS) is a common endocrinopathy that has been associated
with impaired fertility. This chapter reviews the underlying pathophysiology of PCOS and the …
with impaired fertility. This chapter reviews the underlying pathophysiology of PCOS and the …