The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

GG Graham, MJ Davies, RO Day, A Mohamudally… - …, 2013 - Springer
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of
action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors …

Nonopioid medications for pain

D Tauben - Physical Medicine and Rehabilitation Clinics, 2015 - pmr.theclinics.com
Treatment of pain, particularly chronic pain, requires multimodal analgesia that includes
pharmacologic and nondrug therapies as well as a large measure of clinician-guided patient …

Nephrotoxicity in rats exposed to paracetamol: the protective role of moralbosteroid, a steroidal glycoside

G Gupta, DK Chellappan, IS Kikuchi… - Journal of …, 2017 - dl.begellhouse.com
Paracetamol (PCM) has an acceptable safety profile when used at prescribed doses.
However, it is now understood that paracetamol can damage the kidneys when …

Zizyphus jujuba protects against ibuprofen-induced nephrotoxicity in rats

DS Awad, RM Ali, NM Mhaidat… - Pharmaceutical biology, 2014 - Taylor & Francis
Abstract Context. Zizyphus jujuba Mill.(Rhamnaceae) has long been used for the treatment
of anxiety and insomnia in Chinese traditional medicine. The edible part is the fruit. Different …

[HTML][HTML] Eucalyptus globulus extract protects upon acetaminophen-induced kidney damages in male rat

S Dhibi, S Mbarki, A Elfeki, N Hfaiedh - Bosnian Journal of Basic …, 2014 - ncbi.nlm.nih.gov
Plants have historically been used in treating many diseases. Eucalyptus globules, a rich
source of bioactive compounds, and have been shown to possess antioxidative properties …

Anti-inflammatory and antihyperalgesic effects of the combination of ibuprofen and hemin in adjuvant-induced arthritis in the Wistar rat

S Kaur, KRV Bijjem, PL Sharma - Inflammopharmacology, 2011 - Springer
Aim Although, pharmacological activation of heme oxygenase (HO)-1 has shown to produce
ameliorative effects in various experimental models of inflammation, but such beneficial …

Epidemiology of potential drug-drug interactions in hospitalized patients with type 2 diabetes mellitus in China: a retrospective study

W Ren, Y Liu, H Jiang, X Lv, N Zhang - Frontiers in Endocrinology, 2024 - frontiersin.org
Background: Combination therapy was associated with an increased risk of drugdrug
interactions (DDIs) in patients with type 2 diabetes mellitus (T2DM). The present study aimed …

Nephroprotective and antioxidant properties of Artemisia arborescens hydroalcoholic extract against oestroprogestative-induced kidney damages in rats

S Dhibi, H Bouzenna, N Samout, Z Tlili, A Elfeki… - Biomedicine & …, 2016 - Elsevier
Objective Currently, medicinal plants are found to have biological and pharmacological
activities and are used in various domains. This study, carried out on Wistar rats, evaluates …

Клиническая фармакология нестероидных противовоспалительных средств

ЕА Ушкалова, СК Зырянов, АП Переверзев - 2018 - elibrary.ru
В пособии освещена история создания нестероидных противовоспалительных средств
(НПВС) и принципы их классификации. Приведена подробная характеристика …

[PDF][PDF] Potential role of Moringa Oleifera in alleviating paracetamol-induced nephrotoxicity in rat

AA Hegazy, EA Abd Al Hameed, DI El-Wafaey… - Eur. J. Anat, 2020 - eurjanat.com
The kidney plays a vital role in eliminating the toxic substances and drug metabolites from
blood. Therefore, it is prone to hazards in case of abuse or overdose of drugs. The aim of the …