Persistent organic pollutants comprised of organic chemicals like polychlorinated biphenyls,
dibenzo-p-dioxins, dibenzofurans and organochlorinated pesticides which have many …

For the appropriate protection of human health it is necessary to accurately estimate the
health effects of human exposure to toxic compounds. In the present review, epidemiological …

Pesticides almost always occur in mixtures with other ones. The toxicological effects of low-
dose pesticide mixtures on the human health are largely unknown, although there are …

Organochlorine and organophosphate pesticides are compounds that can be detected in
human populations as a result of occupational or residential exposure. Despite their …

Human exposure to pesticides can be estimated through different approaches. The
approach adopted in this study is based on internal dose measures. Studies published …

There has been a steep increase in the prevalence of dementia in recent decades, which
has roughly followed an increase in pesticide use some decades earlier, a time when it is …

Cardiovascular diseases (CVDs) remain the leading cause of death in the developed
countries. Taking into account the mounting evidence about the role of cytochrome P450 …

Metabolic activation of pesticides in the liver may result in highly reactive intermediates
capable of impairing various cellular functions. Nevertheless, the knowledge about the effect …

Extensive research has been carried out to understand and elucidate the mechanisms of
paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular …

The association between genetic variations in the cytochrome P450 (CYP) family genes and
pathological conditions related to long-term exposure to organochlorine compounds (OCs) …