Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid derived in
methionine metabolism. The increased level of Hcy in plasma, hyperhomocysteinemia, is …

Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic
homocysteine in the plasma. The plasma concentration of homocysteine is 5–15 μmol/L in …

Metabolism of excess methionine (Met) to homocysteine (Hcy) by transmethylation is
facilitated by the expression of methionine adenosyltransferase (MAT) I/III and glycine N …

Pediatric cataract is a leading cause of childhood blindness. Untreated cataracts in children
lead to tremendous social, economical, and emotional burden to the child, family, and …

Homocysteine, an amino acid containing a sulfhydryl group, is an intermediate product
during metabolism of the amino acids methionine and cysteine. Hyperhomocysteinemia is …

Inborn errors of metabolism (IEMs) are a group of inherited metabolic disorders which are
caused by mutations in the specific genes that lead to impaired proteins or enzymes …

Inborn errors of metabolism (IEMs) are characterized by deficits in metabolic enzymes as a
result of an inherited disease, leading to the accumulation or decreased excretion of …

Background Betaine is known to act against various biological stresses and its levels were
reported to be decreased in schizophrenia patients. We aimed to test the role of betaine in …

The role of betaine in the liver and kidney has been well documented, even from the cellular
and molecular point of view. Despite literature reporting positive effects of betaine …

Recent advances in engineered bacterial therapeutics underscore their potential in treating
diseases via targeted, live interventions. Despite their promising performance in early …