Anticancer profile of rhodanines: Structure–activity relationship (SAR) and molecular targets—A review

J Szczepański, H Tuszewska, N Trotsko - Molecules, 2022 - mdpi.com
The rhodanine core is a well-known privileged heterocycle in medicinal chemistry. The
rhodanines, as subtypes of thiazolidin-4-ones, show a broad spectrum of biological activity …

Human health-related properties of chromones: an overview

A Nazhand, A Durazzo, M Lucarini… - Natural product …, 2020 - Taylor & Francis
Natural compounds occurring throughout the world are scientifically and practically valuable
because of their unique and beneficial properties to control a wide range of disorders in the …

Pyrano [2, 3-b] chromone derivatives as novel dual inhibitors of α-glucosidase and α-amylase: Design, synthesis, biological evaluation, and in silico studies

E Farzaneh, M Mohammadi, P Raymand, M Noori… - Bioorganic …, 2024 - Elsevier
Inhibition of α-glucosidase and α-amylase is an important target for treatment of type 2
diabetes. In this work, a novel series of pyrano [2, 3-b] chromene derivatives 5a-m was …

Extraction, purification and radioiodination of Khellin as cancer theranostic agent

AA Selim, BM Essa, IM Abdelmonem, MA Amin… - Applied Radiation and …, 2021 - Elsevier
Khellin was successfully extracted from Ammi visnaga fruits with a recovery percent of
96.15%. Next radio-iodination of Khellin was successfully achieved with a high yield. The …

Novel 3‐aryl‐5‐substituted‐coumarin analogues: Synthesis and bioactivity profile

E Kavetsou, A Katopodi, L Argyri… - Drug Development …, 2020 - Wiley Online Library
Abstract Eighteen 3‐aryl‐5‐substituted‐coumarins—six 5‐acetyloxy‐derivatives, six 5‐
hydroxy‐derivatives, and six 5‐geranyloxy‐derivatives—were synthesized, structurally …

[PDF][PDF] Bioactivity study of thiophene and pyrazole containing heterocycles

NV Kale, SP Salve, BK Karale, SD Mhaske… - Orient. J …, 2021 - academia.edu
Chalcones 3a-f were prepared by reacting thiophene containing pyrazolyl aldehyde (2) with
different 2-hydroxy acetophenones 1a-f. The compounds 3a-f were transformed into different …

One‐Pot Synthesis of Novel Furochromone and Oxazocine Derivatives as Promising Antitumor Agents with Their Molecular Docking Studies

RM Borik - Journal of Chemistry, 2020 - Wiley Online Library
One‐pot efficient synthesis of novel chromone derivatives 4a–h and that of 5a–h were
described in a simple method via four‐component reaction between furochromone …