Thiazole-containing compounds as therapeutic targets for cancer therapy

PC Sharma, KK Bansal, A Sharma, D Sharma… - European journal of …, 2020 - Elsevier
In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

Thiazole in the targeted anticancer drug discovery

A Ayati, S Emami, S Moghimi… - Future medicinal …, 2019 - Taylor & Francis
Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …

Recent development in indole derivatives as anticancer agent: A mechanistic approach

N Devi, K Kaur, A Biharee… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Background: Cancer accounts for several deaths each year. There are multiple FDA
approved drugs for cancer treatments. Due to the severe side effects and multiple drug …

Recent advances of thiazole hybrids in biological applications

M Gümüş, M Yakan, İ Koca - Future Medicinal Chemistry, 2019 - Taylor & Francis
Thiazoles have attracted much synthetic interest due to their wide variety of biological
properties and are important members of heterocyclic compounds. In recent years, studies …

[HTML][HTML] Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines

M Hawash, DC Kahraman, SG Ergun, R Cetin-Atalay… - BMC chemistry, 2021 - Springer
Background Liver cancer is predicted to be the sixth most diagnosed cancer globally and
fourth leading cause of cancer deaths. In this study, a series of indole-3-isoxazole-5 …

[HTML][HTML] Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development

A Parthasarathy, EJ Borrego, MA Savka… - Journal of Biological …, 2021 - ASBMB
For millennia, humanity has relied on plants for its medicines, and modern pharmacology
continues to reexamine and mine plant metabolites for novel compounds and to guide …

Novel indole-pyrazole hybrids as potential tubulin-targeting agents; Synthesis, antiproliferative evaluation, and molecular modeling studies

M Hawash, SG Ergun, DC Kahraman, A Olgac… - Journal of Molecular …, 2023 - Elsevier
Abstract Structurally diverse indole-3-pyrazole-5-carboxamide analogues (10-29) were
designed, synthesized, and evaluated for their antiproliferative activity against three cancer …

Anticancer potential of thiazole derivatives: a retrospective review

S Jain, S Pattnaik, K Pathak, S Kumar… - Mini reviews in …, 2018 - ingentaconnect.com
This review brings forth the potential of thiazole derivatives for their anticancer activities. The
emphasis is placed on the structural diversity of thiazole derivatives, responsible for their …

[HTML][HTML] Thiazole ring-the antimicrobial, anti-inflammatory, and anticancer active scaffold

S Hosseininezhad, A Ramazani - Arabian Journal of Chemistry, 2023 - Elsevier
Background Thiazole ring is one of the most important heterocycle scaffolds in organic and
medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …

[PDF][PDF] An overview of microtubule targeting agents for cancer therapy

B Karahalil, S Yardım-Akaydin… - Arhiv za higijenu rada i …, 2019 - hrcak.srce.hr
An overview of microtubule targeting agents for cancer therapy Page 1 160 Karahalil B,
Yardım-Akaydin S, Nacak Baytas S. An overview of microtubule targeting agents for cancer …