Mechanisms of chromium-induced toxicity

TL DesMarias, M Costa - Current opinion in toxicology, 2019 - Elsevier
Chromium is a pervasive environmental contaminant that is of great importance because of
its toxicity. Hexavalent chromium is a classified group 1 carcinogen with multiple complex …

Metals and mechanisms of carcinogenesis

QY Chen, T DesMarais, M Costa - Annual review of …, 2019 - annualreviews.org
Metal exposure is pervasive and not limited to sporadic poisoning events or toxic waste
sites. Hundreds of millions of people around the globe are affected by chronic metal …

The double face of metals: The intriguing case of chromium

G Genchi, G Lauria, A Catalano, A Carocci… - Applied Sciences, 2021 - mdpi.com
Chromium (Cr) is a common element in the Earth's crust. It may exist in different oxidation
states, Cr (0), Cr (III) and Cr (VI), with Cr (III) and Cr (VI) being relatively stable and largely …

Arsenic toxicity: sources, pathophysiology and mechanism

SY Ganie, D Javaid, YA Hajam… - Toxicology Research, 2024 - academic.oup.com
Background Arsenic is a naturally occurring element that poses a significant threat to human
health due to its widespread presence in the environment, affecting millions worldwide …

Maternal cadmium, iron and zinc levels, DNA methylation and birth weight

AC Vidal, V Semenova, T Darrah, A Vengosh… - BMC Pharmacology and …, 2015 - Springer
Abstract Background Cadmium (Cd) is a ubiquitous and environmentally persistent toxic
metal that has been implicated in neurotoxicity, carcinogenesis and obesity and essential …

Role of genomic instability in arsenic-induced carcinogenicity. A review

P Bhattacharjee, M Banerjee, AK Giri - Environment international, 2013 - Elsevier
Exposure to chronic arsenic toxicity is associated with cancer. Although unstable genome is
a characteristic feature of cancer cells, the mechanisms leading to genomic instability in …

Interactions between chromium (III) and iron (III), molybdenum (III) or nickel (II): Cytotoxicity, genotoxicity and mutagenicity studies

S Terpilowska, AK Siwicki - Chemosphere, 2018 - Elsevier
The aim of this study was to examine the effect of chromium (III) and iron (III) and
molybdenum (III) and nickel (II) and their combinations on cyto-, genotoxicity and …

[HTML][HTML] Dysregulation of microRNAs in metal-induced angiogenesis and carcinogenesis

L Wang, LZ Liu, BH Jiang - Seminars in cancer biology, 2021 - Elsevier
MicroRNAs (miRNAs) are small endogenous non-coding RNAs that regulate cancer
initiation, development, angiogenesis, and therapeutic resistance. Metal exposure widely …

Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic

AA Cronican, NF Fitz, A Carter, M Saleem, S Shiva… - PloS one, 2013 - journals.plos.org
Chronic exposure to arsenic in drinking water, especially in utero or perinatal exposure, can
initiate neurological and cognitive dysfunction, as well as memory impairment. Several …

Traffic-derived particulate matter exposure and histone H3 modification: a repeated measures study

Y Zheng, M Sanchez-Guerra, Z Zhang, BT Joyce… - Environmental …, 2017 - Elsevier
Background Airborne particulate matter (PM) may induce epigenetic changes that potentially
lead to chronic diseases. Histone modifications regulate gene expression by influencing …