Medulloblastoma is a heterogeneous embryonal tumor of the cerebellum comprised of four
distinct molecular subgroups that differ in their developmental origins, genomic landscapes …

Objective To investigate the prevalence and trends of essential study design elements in
preclinical urological studies, as well as key factors that may improve methodological rigour …

Genetic modifications during development of paediatric groups 3 and 4 medulloblastoma
are responsible for their highly metastatic properties and poor patient survival rates …

G-protein coupled receptor kinase 2 (GRK2; ADRBK1, BARK1) is most known as a regulator
of G-protein coupled receptors. However, GRK2 also has other functions. Medulloblastomas …

This article presents the frequency of distribution of editorial members of Dove Medical
press, across the world based on their official stated affiliations. Uneven distributions across …

Aims: Methodological rigour enhances reproducibility in preclinical studies and translation
from preclinical to clinical studies. We aimed to investigate the prevalence and the trends of …

Multi-omic technologies have allowed for comprehensive profiling of patient-derived tumor
samples and the cell lines that are intended to model them. Yet, our understanding of how …

Molecular subgrouping of medulloblastoma (MB) has produced four subgroups: wingless
(WNT), sonic hedgehog (SHH), group 3, and group 4. While patients with WNT tumors have …