Regulation of the master regulator FOXM1 in cancer
GB Liao, XZ Li, S Zeng, C Liu, SM Yang, L Yang… - Cell Communication and …, 2018 - Springer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …
FOXM1 and cancer: faulty cellular signaling derails homeostasis
Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
IFNα potentiates anti–PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment
B Hu, M Yu, X Ma, J Sun, C Liu, C Wang, S Wu, P Fu… - Cancer Discovery, 2022 - AACR
The overall response rate for anti–PD-1 therapy remains modest in hepatocellular
carcinoma (HCC). We found that a combination of IFNα and anti–PD-1–based …
carcinoma (HCC). We found that a combination of IFNα and anti–PD-1–based …
The latest advances in the reproductive toxicity of microcystin-LR
S Zhang, X Du, H Liu, MD Losiewic, X Chen, Y Ma… - Environmental …, 2021 - Elsevier
Abstract Microcystin-LR (MC-LR) is an emerging environmental pollutant produced by
cyanobacteria that poses a threat to wild life and human health. In recent years, the …
cyanobacteria that poses a threat to wild life and human health. In recent years, the …
ALKBH5-m6A-FOXM1 signaling axis promotes proliferation and invasion of lung adenocarcinoma cells under intermittent hypoxia
Y Chao, J Shang, W Ji - Biochemical and biophysical research …, 2020 - Elsevier
Obstructive sleep apnea (OSA) is closely associated with cancer progression and cancer-
related mortality. N6-methyladenosine (m 6 A) is involved in the process of intermittent …
related mortality. N6-methyladenosine (m 6 A) is involved in the process of intermittent …
Downregulation of FOXO3a by DNMT1 promotes breast cancer stem cell properties and tumorigenesis
H Liu, Y Song, H Qiu, Y Liu, K Luo, Y Yi… - Cell Death & …, 2020 - nature.com
Breast cancer stem cells (BCSCs) are tumor initiating cells that can self-renew and are
highly tumorigenic and chemoresistant. Therefore, the identification of factors critical for …
highly tumorigenic and chemoresistant. Therefore, the identification of factors critical for …
FOXM1 promotes hepatocellular carcinoma progression by regulating KIF4A expression
G Hu, Z Yan, C Zhang, M Cheng, Y Yan… - Journal of Experimental …, 2019 - Springer
Abstract Background Forkhead box M1 (FOXM1) is a proliferation-associated transcription
factor of the forkhead box proteins superfamily, which includes four isoforms FOXM1a, b, c …
factor of the forkhead box proteins superfamily, which includes four isoforms FOXM1a, b, c …
[HTML][HTML] Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer
J Huang, J Wang, H He, Z Huang, S Wu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Abnormal lipid metabolism including synthesis, uptake, modification, degradation and
transport has been considered a hallmark of malignant tumors and contributes to the supply …
transport has been considered a hallmark of malignant tumors and contributes to the supply …
[HTML][HTML] Drugging the 'undruggable'. Therapeutic targeting of protein–DNA interactions with the use of computer-aided drug discovery methods
Transcription factors (TFs) act as major oncodrivers in many cancers and are frequently
regarded as high-value therapeutic targets. The functionality of TFs relies on direct protein …
regarded as high-value therapeutic targets. The functionality of TFs relies on direct protein …
FOXM1 promotes proliferation in human hepatocellular carcinoma cells by transcriptional activation of CCNB1
N Chai, H Xie, J Yin, Y Guo, M Wang, J Liu… - Biochemical and …, 2018 - Elsevier
The transcription factor Forkhead box protein M1 (FOXM1) plays critical roles in cancer
development and progression, including human hepatocellular carcinoma (HCC). However …
development and progression, including human hepatocellular carcinoma (HCC). However …