Simple Summary Hypercoagulability has been demonstrated to have a strong association
with cancer. It may result in sterile thrombotic cardiac vegetations known as “non-bacterial …

This paper reviews the current evidence on the pathogenesis, clinical manifestations,
diagnosis and management of cancer-associated non-bacterial thrombotic endocarditis …

Aims Endocarditis accounts for significant morbidity and mortality. Timely diagnosis and
prompt treatment are of paramount importance for optimal patient outcome. However, only …

Background The first description of sterile vegetations on the heart valves was provided by
Zeigler in 1888. 1 Libman and Sacks then published a case series of four patients in 1924 …

Background Infective endocarditis (IE) is more common in patients with cancer as compared
with the general population. Due to an immunocompromised state, the need for invasive …

Patients with autoimmune diseases such as systemic lupus erythematosus (SLE) or
antiphospholipid syndrome (APS) are at a higher risk for adverse cardiovascular events …

Infective endocarditis (IE) is increasingly prevalent in the elderly, particularly due to the
rising frequency of invasive procedures and intracardiac devices placed on these …

Animal models of Staphylococcus aureus infective endocarditis (IE), especially in rodents,
are commonly used to investigate the underlying pathogenesis, disease progression …

Sterile vegetations of the cardiac valves were first identified in 1888 by Zeigler, with case
reports described eponymously in 1924 by Libman and Sacks. 1 2 These and subsequent …

Background Non-bacterial thrombotic endocarditis (NBTE) is a rare form of endocarditis
notably described in patients with advanced malignancy and auto-immune diseases. It is …