Lactate from the tumor microenvironment-A key obstacle in NK cell-based immunotherapies

M Jedlička, T Feglarova, L Janstova… - Frontiers in …, 2022 - frontiersin.org
Recent findings about the new roles of lactate have changed our understanding of this end
product of glycolysis or fermentation that was once considered only a waste product. It is …

Glyoxalase 1 inhibitor BBGC suppresses the progression of chronic lymphocytic leukemia and promotes the efficacy of Palbociclib

J Tang, J Zhong, Z Yang, Q Su, W Mo - Biochemical and Biophysical …, 2023 - Elsevier
Chronic lymphocytic leukemia (CLL) is a highly heterogeneous disease. Despite recent
tremen-dous progress in managing CLL, the disease remains incurable with clinical …