CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database

BP Alcock, AR Raphenya, TTY Lau… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Comprehensive Antibiotic Resistance Database (CARD; https://card. mcmaster.
ca) is a curated resource providing reference DNA and protein sequences, detection models …

MEGARes 2.0: a database for classification of antimicrobial drug, biocide and metal resistance determinants in metagenomic sequence data

E Doster, SM Lakin, CJ Dean, C Wolfe… - Nucleic acids …, 2020 - academic.oup.com
Antimicrobial resistance (AMR) is a threat to global public health and the identification of
genetic determinants of AMR is a critical component to epidemiological investigations. High …

[HTML][HTML] Metagenomic-based surveillance systems for antibiotic resistance in non-clinical settings

S Pillay, D Calderón-Franco, A Urhan… - Frontiers in …, 2022 - frontiersin.org
The success of antibiotics as a therapeutic agent has led to their ineffectiveness. The
continuous use and misuse in clinical and non-clinical areas have led to the emergence and …

MEGARes and AMR++, v3. 0: an updated comprehensive database of antimicrobial resistance determinants and an improved software pipeline for classification using …

N Bonin, E Doster, H Worley, LJ Pinnell… - Nucleic acids …, 2023 - academic.oup.com
Antimicrobial resistance (AMR) is considered a critical threat to public health, and
genomic/metagenomic investigations featuring high-throughput analysis of sequence data …

[HTML][HTML] HMD-ARG: hierarchical multi-task deep learning for annotating antibiotic resistance genes

Y Li, Z Xu, W Han, H Cao, R Umarov, A Yan, M Fan… - Microbiome, 2021 - Springer
Background The spread of antibiotic resistance has become one of the most urgent threats
to global health, which is estimated to cause 700,000 deaths each year globally. Its …

The association between insertion sequences and antibiotic resistance genes

M Razavi, E Kristiansson, CF Flach, DGJ Larsson - Msphere, 2020 - Am Soc Microbiol
Insertion sequences (ISs) are abundant mobile genetic elements on bacterial genomes,
responsible for mobilization of many genes, including antibiotic resistance genes (ARGs). As …

Progressing antimicrobial resistance sensing technologies across human, animal, and environmental health domains

KJ Fitzpatrick, HJ Rohlf, TD Sutherland, KM Koo… - ACS …, 2021 - ACS Publications
The spread of antimicrobial resistance (AMR) is a rapidly growing threat to humankind on
both regional and global scales. As countries worldwide prepare to embrace a One Health …

[HTML][HTML] Machine learning algorithm to characterize antimicrobial resistance associated with the International Space Station surface microbiome

P Madrigal, NK Singh, JM Wood, E Gaudioso… - Microbiome, 2022 - Springer
Background Antimicrobial resistance (AMR) has a detrimental impact on human health on
Earth and it is equally concerning in other environments such as space habitat due to …

[HTML][HTML] Survey of drug resistance associated gene mutations in Mycobacterium tuberculosis, ESKAPE and other bacterial species

A Ghosh, SN, S Saha - Scientific reports, 2020 - nature.com
Tuberculosis treatment includes broad-spectrum antibiotics such as rifampicin, streptomycin
and fluoroquinolones, which are also used against other pathogenic bacteria. We …

AMR-meta: a k-mer and metafeature approach to classify antimicrobial resistance from high-throughput short-read metagenomics data

S Marini, M Oliva, IB Slizovskiy, RA Das… - …, 2022 - academic.oup.com
Background Antimicrobial resistance (AMR) is a global health concern. High-throughput
metagenomic sequencing of microbial samples enables profiling of AMR genes through …