Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …

Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …

Self-microemulsifying drug delivery system (SMEDDS) has emerged as a vital strategy to
formulate poor water soluble compounds for bioavailability enhancement. However, certain …

The discovery of new drug molecules depends on a number of steps, which limits the
development of feasible new drugs for the treatment of disease without any side effects …

Self-emulsifying drug delivery system (SEDDS) is an isotropic mixture of lipid, surfactant and
co-surfactant, which forms a fine emulsion when comes in contact of an aqueous medium …

In this study, we select naproxen (NAP) as a reference drug and electrospun poly (ɛ-
caprolactone)(PCL) nanofibers as a fibrous matrix for our drug-delivery system. NAP was …

Introduction: Lipid-based drug delivery systems (LBDDS) are the most promising technique
to formulate the poorly water soluble drugs. Nanotechnology strongly influences the …

Self-emulsifying drug delivery systems (SEDDS) offer potential for overcoming the inherent
slow dissolution and poor oral absorption of hydrophobic drugs by retaining them in a …

Background The oral route is the most popular route for the clinical administration of drugs to
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …