Neuropeptide Y (NPY) is a highly conserved neuropeptide with orexigenic actions in
discrete hypothalamic nuclei that plays a role in regulating energy homeostasis. NPY …

BACKGROUND The global rise in the prevalence of obesity and associated comorbidities
such as type 2 diabetes, cardiovascular disease, and cancer represents a major public …

Selenoproteins contain the essential trace element selenium, the deficiency of which is
associated with cancer or accelerated aging. Although selenoproteins are thought to be …

Despite sequence information from many vertebrates the evolution of the neuropeptide Y
(NPY) family of peptides has been difficult to resolve, particularly among ray-finned fishes …

In mammals, hypothalamic control of food intake involves counterregulation of appetite by
anorexigenic peptides such as corticotropin‐releasing factor (CRF), and orexigenic peptides …

While neuropeptide Y (NPY) has been studied extensively per its pronounced role in food
intake stimulation as well as its role in central pathways governing eating disorders, it has to …

Aversive learning is fundamental for animals to increase chances of survival. In addition to
classical neurotransmitters, neuropeptides have emerged to modulate such complex …

Understanding the complex action mechanism of appetite regulation peptides can
significantly impact therapeutic options in the treatment of obesity and other metabolic …

Protein posttranslational processing is a cellular mechanism fundamental to the generation
of bioactive peptides, including the anorectic α-melanocyte-stimulating hormone (α-MSH) …

CVD (cardiovascular disease) represents a leading cause of mortality in chronic SCI (spinal
cord injury). Several component risk factors are observed in SCI; however, the underlying …