Hepcidin, the iron-regulatory hormone, determines plasma iron concentrations and total
body iron content. Hepcidin, secreted by hepatocytes, functions by controlling the activity of …

Cancer and chemotherapy-induced anemia (CIA) is commonly encountered among patients
undergoing active chemotherapy with or without radiation therapy. Its pathogenesis is …

During its evolution, cancer induces changes in patients' energy metabolism that strongly
affect the overall clinical state and are responsible for cancer-related cachexia syndrome. To …

Iron, an essential trace element, plays a complex role in tumour biology. While iron causes
cancer clearance through toxic free radical generation, iron‐induced free radical flux also …

Cancer is often accompanied by worsening of the patient's iron profile, and the resulting
anemia could be a factor that negatively impacts antineoplastic treatment efficacy and …

Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer.
However, only a portion of patients respond to such treatments. Therefore, it remains a …

Anemia in cancer patients is a relevant condition complicating the course of the neoplastic
disease. Overall, we distinguish the anemia which arises under chemotherapy as pure …

Background Cancer is becoming the most common global public health concern. Early
malnutrition detection and treatment in patients with cancer is an important aspect of cancer …

Cancer-related anemia (CRA) is a complicated and multifaceted problem that can occur as a
result of tumor, as an adverse reaction of chemotherapeutic agent, or as a result of …

Purpose Emerging biomarkers of cancer cachexia and their roles in sarcopenia and
prognosis are poorly understood. Baseline assessments of anthropometrics, sarcopenia …