Atrial fibrillation (AF) is an extremely common clinical problem associated with increased
morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation …

Atrial fibrillation (AF) is an extremely prevalent arrhythmia that presents a wide range of
therapeutic challenges. AF usually begins in a self-terminating paroxysmal form (pAF). With …

Cardiac arrhythmias are a significant cause of morbidity and mortality worldwide, accounting
for 10% to 15% of all deaths. Although most arrhythmias are due to acquired heart disease …

The influence of the central nervous system and autonomic system on cardiac activity is
being intensively studied, as it contributes to the high rate of cardiologic comorbidities …

Kv1. 1 belongs to the Shaker subfamily of voltage-gated potassium channels and acts as a
critical regulator of neuronal excitability in the central and peripheral nervous systems …

Mutations in the KCNA1 gene, which encodes voltage-gated Kv1. 1 potassium channel α-
subunits, cause a variety of human diseases, complicating simple genotype–phenotype …

Abstracts Atrial fibrosis, the hallmark of structural remodeling associated with atrial fibrillation
(AF), is characterized by abnormal proliferation of atrial fibroblasts and excessive deposition …

Objective Identification of epilepsy patients with elevated risk for atrial fibrillation (AF) is
critical given the heightened morbidity and premature mortality associated with this …

Pathophysiological conditions, such as myocardial infarction and mechanical overload affect
the mammalian heart integrity, leading to a stiffened fibrotic tissue. With respect to the …

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related
mortality, but the precise cellular substrates involved remain elusive. Epilepsy-associated …