[HTML][HTML] Metal-organic frameworks for advanced drug delivery

S He, L Wu, X Li, H Sun, T Xiong, J Liu, C Huang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Abstract Metal-organic frameworks (MOFs), comprised of organic ligands and metal
ions/metal clusters via coordinative bonds are highly porous, crystalline materials. Their …

[HTML][HTML] Safe nanoparticles: are we there yet?

W Najahi-Missaoui, RD Arnold… - International journal of …, 2020 - mdpi.com
The field of nanotechnology has grown over the last two decades and made the transition
from the benchtop to applied technologies. Nanoscale-sized particles, or nanoparticles …

Organelle-targeted photosensitizers for precision photodynamic therapy

R Wang, X Li, J Yoon - ACS Applied Materials & Interfaces, 2021 - ACS Publications
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …

Targeting microbial biofilms: current and prospective therapeutic strategies

H Koo, RN Allan, RP Howlin, P Stoodley… - Nature Reviews …, 2017 - nature.com
Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …

Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date

D Bobo, KJ Robinson, J Islam, KJ Thurecht… - Pharmaceutical …, 2016 - Springer
In this review we provide an up to date snapshot of nanomedicines either currently approved
by the US FDA, or in the FDA clinical trials process. We define nanomedicines as …

Cancer cell membrane–biomimetic nanoparticles for homologous-targeting dual-modal imaging and photothermal therapy

Z Chen, P Zhao, Z Luo, M Zheng, H Tian, P Gong… - ACS …, 2016 - ACS Publications
An active cell membrane–camouflaged nanoparticle, owning to membrane antigens and
membrane structure, can achieve special properties such as specific recognition, long blood …

Immunomodulatory nanosystems

X Feng, W Xu, Z Li, W Song, J Ding… - Advanced science, 2019 - Wiley Online Library
Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

E Pérez-Herrero, A Fernández-Medarde - European journal of …, 2015 - Elsevier
Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …

Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …