Glycans, carbohydrate molecules in the realm of biology, are present as biomedically
important glycoconjugates and a characteristic aspect is that their structures in many …

Glycans are key players in many biological processes. They are essential for protein folding
and stability and act as recognition elements in cell–cell and cell–matrix interactions. Thus …

Highlights•NMR methods are of paramount importance to deduce structure, dynamics and
recognition of complex glycans.•The intrinsic low sensitivity of NMR for studying glycans and …

This perspective article is focused on the presentation of the latest advances in NMR
methods and applications that are behind the exciting achievements in the understanding of …

The diversity of the cellular proteome substantially exceeds the number of genes coded by
the DNA of an organism because one or more residues in a majority of eukaryotic proteins …

Compared to soluble protein counterparts, the understanding of membrane protein stability,
solvent interactions, and function are not as well understood. Recent advancements in …

Protein N-glycosylation stands out for its intrinsic and functionally related heterogeneity.
Despite its biomedical interest, Glycoprofile analysis still remains a major scientific …

The Fc portion of immunoglobulin G (IgG) is a horseshoe-shaped homodimer, which
interacts with various effector proteins, including Fcγ receptors (FcγRs). These interactions …

As structural biology trends towards larger and more complex biomolecular targets, a
detailed understanding of their interactions and underlying structures and dynamics is …

Integral membrane proteins (IMPs) perform unique and indispensable functions in the cell,
making them attractive targets for fundamental research and drug discovery. Developments …