Membrane lipids and proteins are non-randomly distributed and are unable to diffuse freely
in the plane of the membrane. This is because of multiple constraints imposed both by the …

▪ Abstract This review summarizes key aspects of tetraspanin proteins, with a focus on the
functional relevance and structural features of these proteins and how they are organized …

The tetraspanin transmembrane proteins have emerged as key players in malignancy, the
immune system, during fertilization and infectious disease processes. Tetraspanins engage …

The tetraspanin CD9 is expressed by all the major subsets of leukocytes (B cells, CD4+ T
cells, CD8+ T cells, natural killer cells, granulocytes, monocytes and macrophages, and …

The hematopoietic system is an invaluable model both for understanding basic
developmental biology and for developing clinically relevant cell therapies. Using highly …

In somatic cells, the tetraspanins CD81 and CD9 associate with each other, with additional
tetraspanins and with non-tetraspanin molecules to form proteolipidic complexes. Here we …

Tetraspanins associate with several transmembrane proteins forming microdomains
involved in intercellular adhesion and migration. Here, we show that endothelial …

The mechanisms driving the development of extracapillary lesions in focal segmental
glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) remain poorly …

CD36 is a versatile receptor known to play a central role in the development of
atherosclerosis, the pathogenesis of malaria, and the removal of apoptotic cells …

In the present minireview, we intend to provide a brief history of the field of CD9 involvement
in oncogenesis and in the metastatic process of cancer, considering its potential value as a …