Studies of neuropeptide and peptide hormone signaling are coming of age in Drosophila
due to rapid developments in molecular genetics approaches that overcome the difficulties …

Neuropeptides in insects act as neuromodulators in the central and peripheral nervous
system and as regulatory hormones released into the circulation. The functional roles of …

Neuropeptides are signaling molecules that commonly act via G protein-coupled receptors
(GPCRs) and are generated in neurons by proneuropeptide (pNP) cleavage. Present in both …

Neuropeptides play critical roles in synaptic signaling in all nervous systems. Unlike
classical neurotransmitters, peptidergic neurotransmitters are encoded as preproproteins …

Functional studies of cotransmission. Page 1 PHYSIOLOGICAL REVIEWS Vol. ‘71, No. 3,
July 1991 Prided in USA Functional Studies of. Cotransmission IRVING KUPFERMANN …

Neuropeptides, representing the largest class of neuromodulators, commonly signal by G-
protein-coupled receptors (GPCRs). While the neuropeptide repertoire of several metazoans …

The marine mollusc Aplysia californica carries out biting, swallowing, and rejection
responses using different movements of its radula, a structure that is used to grasp and …

In 1928 Ernst Scharrer first presented evidence that nerve cells in the hypothalamus of the
minnow, Phloxinus laevis, have the cytological characteristics of secretory cells (Sharrer …

We have investigated the release of two peptide cotransmitters from the terminals of a
cholinergic motor neuron in Aplysia. Identified motor neuron B15 synthesizes the two small …

A major factor in the recognition of the diverse roles of neuropeptides in the nervous system
was the development of radioimmunoassays and immunohistochemistry (see Guillemin …