[HTML][HTML] Experimental and clinical treatment of Chagas disease: a review

PAS Junior, I Molina, SMF Murta… - The American journal …, 2017 - ncbi.nlm.nih.gov
Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million …

Road map to the treatment of neglected tropical diseases: Nanocarriers interventions

G Joshi, SS Quadir, KS Yadav - Journal of Controlled Release, 2021 - Elsevier
Neglected tropical disease (NTD) is a set of 20 deadliest endemic diseases which shows its
presence in most of the developing countries worldwide. Nearly 1 billion of the population …

Influence of the encapsulation efficiency and size of liposome on the oral bioavailability of griseofulvin-loaded liposomes

SGM Ong, LC Ming, KS Lee, KH Yuen - Pharmaceutics, 2016 - mdpi.com
The objective of the present study was to investigate the influence of the encapsulation
efficiency and size of liposome on the oral bioavailability of griseofulvin-loaded liposomes …

Preparation and evaluation of reverse-phase evaporation and multilamellar niosomes as ophthalmic carriers of acetazolamide

AS Guinedi, ND Mortada, S Mansour… - International journal of …, 2005 - Elsevier
Niosomes have been reported as a possible approach to improve the low corneal
penetration and bioavailability characteristics shown by conventional ophthalmic vehicles …

Liposomes as an ocular delivery system for acetazolamide: in vitro and in vivo studies

RM Hathout, S Mansour, ND Mortada, AS Guinedi - AAPS pharmscitech, 2007 - Springer
The purpose of this study was to formulate topically effective controlled release ophthalmic
acetazolamide liposomal formulations. Reverse-phase evaporation and lipid film hydration …

Vesicular aceclofenac systems: a comparative study between liposomes and niosomes

M Nasr, S Mansour, ND Mortada… - Journal of …, 2008 - Taylor & Francis
Vesicular delivery systems have been reported to serve as local depot for sustained drug
release. Aceclofenac multilamellar liposomes and niosomes were prepared and a …

Cosm-nutraceutical nanovesicles for acne treatment: Physicochemical characterization and exploratory clinical experimentation

SS Amer, M Nasr, RTA Abdel-Aziz, NH Moftah… - International journal of …, 2020 - Elsevier
The full exploration of the 'nutraceuticals' therapeutic potential in cosmetics has been
hindered by their poor stratum corneum permeation. Therefore, the aim of the present study …

Formulation of benznidazole-lipid nanocapsules: Drug release, permeability, biocompatibility, and stability studies

EC Arrua, O Hartwig, B Loretz, X Murgia, DK Ho… - International Journal of …, 2023 - Elsevier
Benznidazole, a poorly soluble in water drug, is the first-line medication for the treatment of
Chagas disease, but long treatment periods at high dosages cause several adverse effects …

Solid nanomedicines of nifurtimox and benznidazole for the oral treatment of chagas disease

M Rolon, E Hanna, C Vega, C Coronel… - Pharmaceutics, 2022 - mdpi.com
Chagas disease (CD) is a parasitic zoonosis endemic in Central and South America
affecting nearly 10 million people, with 100 million people at high risk of contracting the …

First century of chagas' disease: An overview on novel approaches to nifurtimox and benznidazole delivery systems

CJ Salomon - Journal of Pharmaceutical Sciences, 2012 - Elsevier
Hundred years after the discovery of Chagas' disease, there is a lack of effective treatment to
control this neglected disease caused by the parasite Trypanosoma cruzi. The transmission …