Role of macrophages in pulmonary arterial hypertension
MQ Zhang, CC Wang, XB Pang, JZ Shi, HR Li… - Frontiers in …, 2023 - frontiersin.org
Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary vascular disease
characterized by progressive pulmonary artery pressure elevation, increased pulmonary …
characterized by progressive pulmonary artery pressure elevation, increased pulmonary …
The role of glutamine and glutaminase in pulmonary hypertension
S Wang, Y Yan, WJ Xu, SG Gong, XJ Zhong… - Frontiers in …, 2022 - frontiersin.org
Pulmonary hypertension (PH) refers to a clinical and pathophysiological syndrome in which
pulmonary vascular resistance and pulmonary arterial pressure are increased due to …
pulmonary vascular resistance and pulmonary arterial pressure are increased due to …
Integrated transcriptomic and metabolomic analysis of cortical neurons reveals dysregulated lipid metabolism, enhanced glycolysis and activated HIF-1 signaling …
W Zhang, B Han, H Zhang, R Fu, Y Lu, G Zhang - Heliyon, 2023 - cell.com
The brain is the main oxygen-consuming organ and is vulnerable to ischemic shock or
insufficient blood perfusion. Brain hypoxia has a persistent and detrimental effect on resident …
insufficient blood perfusion. Brain hypoxia has a persistent and detrimental effect on resident …
Assessing and mitigating batch effects in large-scale omics studies
Y Yu, Y Mai, Y Zheng, L Shi - Genome Biology, 2024 - Springer
Batch effects in omics data are notoriously common technical variations unrelated to study
objectives, and may result in misleading outcomes if uncorrected, or hinder biomedical …
objectives, and may result in misleading outcomes if uncorrected, or hinder biomedical …
Regulatory T cell-related gene indicators in pulmonary hypertension
Y Liu, JZ Shi, R Jiang, SF Liu, YY He… - Frontiers in …, 2022 - frontiersin.org
Objective: Regulatory T cells (Tregs) are critical immune modulators to maintain immune
homeostasis and limit pulmonary hypertension (PH). This study was aimed to identify Treg …
homeostasis and limit pulmonary hypertension (PH). This study was aimed to identify Treg …
Animal models of pulmonary hypertension due to left heart disease
Pulmonary hypertension due to left heart disease (PH‐LHD) is regarded as the most
prevalent form of pulmonary hypertension (PH). Indeed, PH is an independent risk factor …
prevalent form of pulmonary hypertension (PH). Indeed, PH is an independent risk factor …
MicroRNA‐210 mediates hypoxia‐induced pulmonary hypertension by targeting mitochondrial bioenergetics and mtROS flux
Aim Chronic hypoxia is a common cause of pulmonary hypertension (PH). We test the
hypothesis that microRNA‐210 (miR‐210) mediates hypoxia‐induced PH by targeting …
hypothesis that microRNA‐210 (miR‐210) mediates hypoxia‐induced PH by targeting …
Metabolic reprogramming: A novel metabolic model for pulmonary hypertension
X Liu, L Zhang, W Zhang - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Pulmonary arterial hypertension, or PAH, is a condition that is characterized by pulmonary
artery pressures above 20 mmHg (at rest). In the treatment of PAH, the pulmonary vascular …
artery pressures above 20 mmHg (at rest). In the treatment of PAH, the pulmonary vascular …
The role of prolactin/vasoinhibins in cardiovascular diseases
H Zhao, S Gong, Y Shi, C Luo, H Qiu… - Animal Models and …, 2023 - Wiley Online Library
Prolactin (PRL) is a polypeptide hormone that is mainly synthesized and secreted by the
lactotroph cells of the pituitary. There are two main isoforms of PRL: 23‐kDa PRL (named full …
lactotroph cells of the pituitary. There are two main isoforms of PRL: 23‐kDa PRL (named full …
[HTML][HTML] Hypoxia-Induced Mitochondrial ROS and Function in Pulmonary Arterial Endothelial Cells
H Wang, TY Song, J Reyes-García, YX Wang - Cells, 2024 - mdpi.com
Pulmonary artery endothelial cells (PAECs) are a major contributor to hypoxic pulmonary
hypertension (PH) due to the possible roles of reactive oxygen species (ROS). However, the …
hypertension (PH) due to the possible roles of reactive oxygen species (ROS). However, the …