Recent developments in one-pot stepwise synthesis (OPSS) of small molecules

X Ma, W Zhang - Iscience, 2022 - cell.com
One-pot synthesis is an active topic in organic chemistry due to its intrinsic advantages of
simple operation, high mass efficiency, low cost, and less amount of waste disposal. Among …

Synthesis of Trifluoromethylated Pyrazolidines, Pyrazolines and Pyrazoles via Divergent Reaction of β-CF3-1,3-Enynes with Hydrazines

L Wei, S Ding, M Liu, Z Yu, Y Xiao - Organic Letters, 2021 - ACS Publications
Three types of trifluoromethylated pyrazolidines, pyrazolines, and pyrazoles can be
synthesized via divergent reaction of β-CF3-1, 3-enyne with hydrazines. The reaction with …

PEG-mediated synthesis, antibacterial, antifungal and antioxidant studies of some new 1, 3, 5-trisubstituted 2-pyrazolines

SL Dhonnar, BS Jagdale, VA Adole, NV Sadgir - Molecular Diversity, 2023 - Springer
Abstract A new series of 1, 3, 5-trisubstituted 2-pyrazoline derivatives (3a–l) are synthesized
in good to excellent yields from the corresponding chalcones (1a–h) and acid hydrazides …

From 2011 to 2022: The development of pyrazole derivatives through the α,β‐unsaturated carbonyl compounds

S Sharma, V Singh, Vaishali, R Kumar… - Journal of …, 2024 - Wiley Online Library
The synthesis of pyrazole derivative using α, β‐unsaturated carbonyl compounds has
attracted increasing attention of the synthetic organic chemist community. Interestingly, the …

Green and efficient three-component synthesis of novel isoniazid pyrazoles, molecular docking, antioxidant and antitubercular evaluation

BP Koli, RP Gore, PR Malasane - Synthetic Communications, 2023 - Taylor & Francis
A series of novel isoniazid pyrazole derivatives were synthesized by an efficient,
multicomponent reaction of various substituted aromatic aldehydes, isoniazid, and …

تحضير وتشخيص جالكونات وحلقات البايرازولين الجديدة المشتقة من حلقة 3، 1-بنزوديوكسول

HJ Mohammad, MS Hussein - Samarra Journal of Pure and Applied …, 2023 - sjpas.com
This research included the preparation of new pyrazoline rings from chalcones of the 1, 3-
benzodiaoxolo ring with hydrazine and some of its derivatives, In the first step: new …