Therapeutic potential of rosmarinic acid: A comprehensive review

M Nadeem, M Imran, T Aslam Gondal, A Imran… - Applied Sciences, 2019 - mdpi.com
Naturally occurring food-derived active ingredients have received huge attention for their
chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) …

Rosmarinic acid: modes of action, medicinal values and health benefits

M Alagawany, ME Abd El-Hack, MR Farag… - Animal Health …, 2017 - cambridge.org
The supplementation of livestock rations with herbs containing bioactive components, such
as rosmarinic acid (RA), have shown promising results as a natural feed additive in …

The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view

EHM Hassanein, WR Mohamed, OS Ahmed… - Life Sciences, 2022 - Elsevier
Kidney diseases are major health problem and understanding the underlined mechanisms
that lead to kidney diseases are critical research points with a marked potential impact on …

Natural antioxidants in the treatment and prevention of diabetic nephropathy; a potential approach that warrants clinical trials

N Al-Waili, H Al-Waili, T Al-Waili, K Salom - Redox Report, 2017 - Taylor & Francis
Diabetic nephropathy is the major cause of end-stage renal disease and effective and new
therapeutic approaches are needed in diabetic nephropathy and chronic kidney diseases …

Kidney‐Targeted Nanoparticles Loaded with the Natural Antioxidant Rosmarinic Acid for Acute Kidney Injury Treatment

J Li, Q Duan, X Wei, J Wu, Q Yang - Small, 2022 - Wiley Online Library
Acute kidney injury (AKI) is a common clinical disease with high morbidity and mortality, and
with a lack of effective drugs for treatment. Oxidative stress is very important in the …

Rosmarinic acid elicits neuroprotection in ischemic stroke via Nrf2 and heme oxygenase 1 signaling

HY Cui, XJ Zhang, Y Yang, C Zhang… - Neural regeneration …, 2018 - journals.lww.com
Rosmarinic acid (RA) can elicit a neuroprotective effect against ischemic stroke, but the
precise molecular mechanism remains poorly understood. In this study, an experimental …

Rosmarinic acid mitigates chlorpyrifos-induced oxidative stress, inflammation, and kidney injury in rats by modulating SIRT1 and Nrf2/HO-1 signaling

MS Abduh, RS Alruhaimi, HA Alqhtani, OE Hussein… - Life Sciences, 2023 - Elsevier
Chlorpyrifos (CPF) is a widely used broad-spectrum pesticide with multi-organ toxic effects.
Oxidative stress was found to play a role in the deleterious effects of CPF, including …

[HTML][HTML] Antioxidant effect of p-coumaric acid on interleukin 1-β and tumor necrosis factor-α in rats with renal ischemic reperfusion

SM Godarzi, AV Gorji, B Gholizadeh, SA Mard… - Nefrologia, 2020 - Elsevier
Background and aims Renal ischemia-reperfusion occurs in some clinical conditions such
as kidney surgery that can leads to acute renal failure. The aim of this study was to …

Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress

D Zhong, H Wang, M Liu, X Li, M Huang, H Zhou… - Scientific reports, 2015 - nature.com
Ganoderma lucidum polysaccharide peptide (GLPP) scavenges oxygen free radicals that
are a key factor in the pathogenesis of renal ischemia reperfusion injury (RIRI). The aim of …

Rosmarinic acid prevents against memory deficits in ischemic mice

AA Fonteles, CM de Souza, JC de Sousa Neves… - Behavioural Brain …, 2016 - Elsevier
Polyphenols have neuroprotective effects after brain ischemia. It has been demonstrated
that rosmarinic acid (RA), a natural phenolic compound, possesses antioxidant and anti …