Rapid optimization of Mcl-1 inhibitors using stapled peptide libraries including non-natural side chains

R Rezaei Araghi, JA Ryan, A Letai… - ACS chemical …, 2016 - ACS Publications
Alpha helices form a critical part of the binding interface for many protein–protein
interactions, and chemically stabilized synthetic helical peptides can be effective inhibitors of …

[HTML][HTML] “One-pot” fabrication of highly versatile and biocompatible poly (vinyl alcohol)-porphyrin-based nanotheranostics

Y Luo, H Wu, C Feng, K Xiao, X Yang, Q Liu, T Lin… - Theranostics, 2017 - ncbi.nlm.nih.gov
Nanoparticle-based theranostic agents have emerged as a new paradigm in nanomedicine
field for integration of multimodal imaging and therapeutic functions within a single platform …

Bottom-Up Design Approach for OBOC Peptide Libraries

D Kalafatovic, G Mauša, D Rešetar Maslov, E Giralt - Molecules, 2020 - mdpi.com
One-bead-one-compound peptide libraries, developed following the top-down experimental
approach, have attracted great interest in the identification of potential ligands or active …

Synthesis and cell-based screening of one-bead-one-compound peptide libraries

FC Bononi, LG Luyt - Peptide Libraries: Methods and Protocols, 2015 - Springer
Combinatorial one-bead-one-compound (OBOC) peptide library screening has proven to be
a powerful tool for identification of small molecules, peptides, or peptidomimetics against a …

Rapid Discovery of Illuminating Peptides for Instant Detection of Opioids in Blood and Body Fluids

S Jafari, Y Thillier, YH Ajena, D Shorty, J Li, JS Huynh… - Molecules, 2019 - mdpi.com
The United States is currently experiencing an opioid crisis, with more than 47,000 deaths in
2017 due to opioid overdoses. Current approaches for opioid identification and …

Kits for analysis using nucleic acid encoding and/or label

MS Chee, JM Beierle, N Muranaka… - US Patent …, 2024 - Google Patents
2022-09-09 Assigned to Encodia, Inc. reassignment Encodia, Inc. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: CHEE, MARK S …

Methods for preparing analytes and related kits

MS Chee, KL Gunderson, N Muranaka… - US Patent …, 2023 - Google Patents
US11634709B2 - Methods for preparing analytes and related kits - Google Patents
US11634709B2 - Methods for preparing analytes and related kits - Google Patents Methods for …

Kits for analysis using nucleic acid encoding and/or label

MS Chee, JM Beierle, N Muranaka… - US Patent …, 2023 - Google Patents
Kits and methods of using the kits for analyzing macromolecules, including peptides,
polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample …

Macromolecule analysis employing nucleic acid encoding

MS Chee, KL Gunderson, MP Weiner - US Patent 11,959,922, 2024 - Google Patents
US11959922B2 - Macromolecule analysis employing nucleic acid encoding - Google Patents
US11959922B2 - Macromolecule analysis employing nucleic acid encoding - Google Patents …

Guest editorial: funding for innovative cancer-relevant technology development

A Dickherber, B Sorg, R Divi, A Ganguly, M Ossandon - Lab on a Chip, 2014 - pubs.rsc.org
Extraordinary progress has been made in the last several decades in basic and clinical
cancer research, but an urgent need persists for better tools that can accelerate our ability to …