Primary graft failure (PGF) is a devastating complication that occurs in the immediate
postoperative period following heart transplantation. It manifests as severe ventricular …

Objectives Levosimendan is an inotropic drug with organ-protective properties due to its
activation of mitochondrial KATP channels. This prospective, randomized, double-blind …

Objective To ascertain if levosimendan postconditioning can alleviate lung ischemia–
reperfusion injury (LIRI) in rats. Method One hundred rats were divided into five groups …

Background Ischemia-reperfusion injury (IRI) is a major challenge in liver transplantation.
The mitochondrial pathway plays a pivotal role in hepatic IRI. Levosimendan, a calcium …

Levosimendan, a known calcium sensitizer with positive inotropic and vasodilating
properties, might also be cardioprotective during ischemia-reperfusion (I/R) insult. Its effects …

Hintergrund Levosimendan steigert die myokardiale Kontraktilität ohne relevante Erhöhung
des myozytären Sauerstoffverbrauchs und besitzt kardioprotektive Eigenschaften. Es gibt …

Background Levosimendan has been reported to have a positive effect on ischemia–
reperfusion injury. Herein, we aimed to evaluate the effects of levosimendan applied after …

Levosimendan is a calcium-sensitizing agent shown to prevent myocardical contractile
depression in various heart diseases. In this study, we investigated the effect of …

Background: Levosimendan improves resuscitation rates and cardiac performance in animal
cardiac arrest models. The aim of this study was to describe the use of levosimendan in out …

Background: Levosimendan (LEVO), is an inotropic agent which has been shown to be
associated with better myocardial performance, and higher survival rate in cardiac surgical …