XGDAG: explainable gene–disease associations via graph neural networks
Motivation Disease gene prioritization consists in identifying genes that are likely to be
involved in the mechanisms of a given disease, providing a ranking of such genes. Recently …
involved in the mechanisms of a given disease, providing a ranking of such genes. Recently …
Predicting protein functions using positive-unlabeled ranking with ontology-based priors
Automated protein function prediction is a crucial and widely studied problem in
bioinformatics. Computationally, protein function is a multilabel classification problem where …
bioinformatics. Computationally, protein function is a multilabel classification problem where …
[HTML][HTML] On propagation in networks, promising models beyond network diffusion to describe degenerative brain diseases and traumatic brain injuries
D Vergni, P Stolfi, A Pascarella - Frontiers in Pharmacology, 2024 - frontiersin.org
Introduction: Connections among neurons form one of the most amazing and effective
network in nature. At higher level, also the functional structures of the brain is organized as a …
network in nature. At higher level, also the functional structures of the brain is organized as a …
Absolute Value Inequality SVM for the PU Learning Problem
Y Yuan, F Bai - Mathematics, 2024 - mdpi.com
Positive and unlabeled learning (PU learning) is a significant binary classification task in
machine learning; it focuses on training accurate classifiers using positive data and …
machine learning; it focuses on training accurate classifiers using positive data and …
Diagnosis of Parkinson's disease genes using LSTM and MLP-based multi-feature extraction methods
Disease gene identification using computational methods is one of the most challenging
issues to improve the treatment and diagnosis of Parkinson's disease (PD). Various …
issues to improve the treatment and diagnosis of Parkinson's disease (PD). Various …
PUNNHMD A: Microbe-Disease Association prediction based on PU learning and optimized K-Nearest Neighbor algorithm
J Wang, D Lu, L Wang, Y Lin… - 2023 IEEE 11th Joint …, 2023 - ieeexplore.ieee.org
By deepening our understanding of the relationship between microorganisms and disease,
we can study the formation and pathogenesis of various complex diseases. This, in turn …
we can study the formation and pathogenesis of various complex diseases. This, in turn …
Toward explainable biomedical deep learning
A Mastropietro - 2024 - iris.uniroma1.it
Deep learning has been extensively utilized in the domains of bioinformatics and
chemoinformatics, yielding compelling results. However, neural networks have …
chemoinformatics, yielding compelling results. However, neural networks have …