The role and regulation of the NKG2D/NKG2D ligand system in cancer

G Tan, KM Spillane, J Maher - Biology, 2023 - mdpi.com
Simple Summary The immune system provides surveillance measures to identify and
remove damaged cell types at an early stage. One important example involves the NKG2D …

Chimeric Antigen Receptor (CAR) T-Cell therapy for patients with lung cancer: Current perspectives

J Maher - OncoTargets and Therapy, 2023 - Taylor & Francis
Immunotherapy using chimeric antigen receptor (CAR)-engineered T-cells has achieved
unprecedented efficacy in selected hematological cancers. However, solid tumors such as …

A novel human single-domain antibody-drug conjugate targeting CEACAM5 exhibits potent in vitro and in vivo antitumor activity

X Zhu, Q Li, Y Kong, K Huang, G Wang… - Acta Pharmacologica …, 2024 - nature.com
Leveraging the specificity of antibody to deliver cytotoxic agent into tumor, antibody-drug
conjugates (ADCs) have become one of the hotspots in the development of anticancer …

[HTML][HTML] Left out in the cold: moving beyond hormonal therapy for the treatment of immunologically cold prostate cancer with CAR T cell immunotherapies

LH Porter, SG Harrison, GP Risbridger, N Lister… - The Journal of Steroid …, 2024 - Elsevier
Prostate cancer is primarily hormone-dependent, and medical treatments have focused on
inhibiting androgen biosynthesis or signaling through various approaches. Despite …

Advancing lung adenocarcinoma prognosis and immunotherapy prediction with a multi‐omics consensus machine learning approach

H Lin, X Zhang, Y Feng, Z Gong, J Li… - Journal of Cellular …, 2024 - Wiley Online Library
Lung adenocarcinoma (LUAD) is a tumour characterized by high tumour heterogeneity.
Although there are numerous prognostic and immunotherapeutic options available for …

CEACAM5-Targeted Immuno-PET in Androgen Receptor–Negative Prostate Cancer

C Imberti, R De Gregorio, JA Korsen… - Journal of Nuclear …, 2024 - Soc Nuclear Med
The incidence of androgen receptor (AR)–negative (AR−) prostate cancer, including
aggressive neuroendocrine prostate cancer (NEPC), has more than doubled in the last …

L'immunohistochimie c-Met en oncologie thoracique, un nouvel enjeu pour le pathologiste

V Hofman, C Bontoux, S Goffinet, F Murcy… - Revue Francophone des …, 2023 - Elsevier
Résumé Le développement croissant des anticorps conjugués à des molécules
cytotoxiques (ADCs pour Antibody drug conjugates) comme nouvelle stratégie …

Identification of key genes and biological pathways in chronic obstructive pulmonary disease using bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Identification of accurate biomarkers is still particularly urgent for improving the poor survival
of chronic obstructive pulmonary disease (COPD) patients. In this investigation, we aimed to …

[PDF][PDF] The Role of Chemistry in Contribution to Biomedicine Recently. J of Clin Bio Med Adv 3 (4), 01-10

DD Sung - 2024 - mkscienceset.com
The Role of Chemistry in Contribution to Biomedicine Recently Page 1 Journal of Clinical and
Biomedical Advances www.mkscienceset.com J Clin Bio Med Adv 2024 Research Article The …

[PDF][PDF] Rare Adverse Events of CAR T-Cell Therapy

A Müller - healthbook TIMES Oncology …, 2024 - onco-hema.healthbooktimes.org
Chimeric antigen receptor (CAR) T-cell therapy has emerged as a promising treatment
option for various types of cancers. Although it has shown remarkable effectiveness, this …