Antimicrobial resistance prediction in Neisseria gonorrhoeae: current status and future prospects

D Golparian, M Unemo - Expert Review of Molecular Diagnostics, 2022 - Taylor & Francis
Introduction Several nucleic acid amplification tests (NAATs), mostly PCRs, to detect
antimicrobial resistance (AMR) determinants and predict AMR in Neisseria gonorrhoeae are …

Advances in genotypic antimicrobialresistance testing: a comprehensive review

B Duan, X Zeng, J Peng - Science China Life Sciences, 2024 - Springer
Antimicrobial resistance (AMR) represents a substantial threat to global public health,
complicating the treatment of common infections and leading to prolonged illness and …

Application of nanopore sequencing technology in the clinical diagnosis of infectious diseases

LL Zhang, C Zhang, JP Peng - Biomedical and Environmental Sciences, 2022 - Elsevier
Infectious diseases are an enormous public health burden and a growing threat to human
health worldwide. Emerging or classic recurrent pathogens, or pathogens with resistant …

Multiplex PCR and Nanopore Sequencing of Genes Associated with Antimicrobial Resistance in Neisseria gonorrhoeae Directly from Clinical Samples

C Zhang, L Xiu, Y Li, L Sun, Y Li, Y Zeng… - Clinical …, 2021 - academic.oup.com
Background Antimicrobial resistance (AMR) of Neisseria gonorrhoeae has spread
worldwide. Rapid and comprehensive methods are needed to describe N. gonorrhoeae …

Development and application of Cas13a-based diagnostic assay for Neisseria gonorrhoeae detection and azithromycin resistance identification

H Luo, W Chen, Z Mai, J Yang, X Lin… - Journal of …, 2022 - academic.oup.com
Abstract Background Gonorrhoea, caused by Neisseria gonorrhoeae, has spread
worldwide. Strains resistant to most antibiotics, including ceftriaxone and azithromycin, have …

Multicentre clinical evaluation of a molecular diagnostic assay to identify Neisseria gonorrhoeae infection and detect antimicrobial resistance

L Xiu, L Wang, Y Li, L Hu, J Huang, G Yong… - International Journal of …, 2023 - Elsevier
Objectives Antimicrobial resistance (AMR) in Neisseria gonorrhoeae (N. gonorrhoeae) is an
urgent threat to public health, with the emergence of highly resistant strains such as the …

Genomic epidemiology of Neisseria gonorrhoeae in Shenzhen, China, during 2019–2020: increased spread of ceftriaxone-resistant isolates brings insights for …

D Wang, Y Li, C Zhang, Y Zeng, J Peng… - Microbiology …, 2023 - Am Soc Microbiol
The antimicrobial resistance (AMR) in gonorrhea poses global threat of increasing public
health concern. In response to this concern, molecular surveillance has been widely utilized …

Rapid detection of antimicrobial resistance in Mycoplasma genitalium by high-resolution melting analysis with unlabeled probes

Y Li, L Xiu, L Wang, L Zhang, F Wang… - Microbiology …, 2022 - Am Soc Microbiol
With looming resistance to fluoroquinolones in Mycoplasma genitalium, public health control
strategies require effective antimicrobial resistance (AMR) diagnostic methods for clinical …

Alternations of antibiotic resistance genes and microbial community dynamics on shared bicycles before and after pandemic lockdown

L Xiu, H Liu, Y Xie, Q Hu, H Li, F Chen, C Wang… - Science of the Total …, 2024 - Elsevier
The prevalence of shared bicycles has raised concerns over their potential to transmit
pathogens and microbes harboring antibiotic resistance genes (ARGs), which pose …

Loop-Mediated Isothermal Amplification Assay for Identifying Neisseria gonorrhoeae Nonmosaic penA-Targeting Strains Potentially Eradicable by Cefixime

K Shimuta, H Takahashi, Y Akeda… - Microbiology …, 2022 - Am Soc Microbiol
Treatment regimens for gonorrhea have limited efficacy worldwide due to the rapid spread of
antimicrobial resistance. Cefixime (CFM) is currently not recommended as a first-line …