The forgotten people: Hepatitis B virus (HBV) infection as a priority for the inclusion health agenda

E Martyn, S Eisen, N Longley, P Harris, J Surey… - Elife, 2023 - elifesciences.org
Hepatitis B virus (HBV) infection represents a significant global health threat, accounting for
300 million chronic infections and up to 1 million deaths each year. HBV disproportionately …

Systematic review and individual-patient-data meta-analysis of non-invasive fibrosis markers for chronic hepatitis B in Africa

A Johannessen, AJ Stockdale, MYR Henrion… - Nature …, 2023 - nature.com
Abstract In sub-Saharan Africa, simple biomarkers of liver fibrosis are needed to scale-up
hepatitis B treatment. We conducted an individual participant data meta-analysis of 3,548 …

[HTML][HTML] Enhancing interventions for prevention of mother-to-child-transmission of hepatitis B virus

PC Matthews, P Ocama, S Wang, M El-Sayed… - JHEP Reports, 2023 - Elsevier
Prevention of mother-to-child transmission of hepatitis B virus (HBV) infection is a
cornerstone of efforts to support progress towards elimination of viral hepatitis. Current …

A new approach to prevent, diagnose, and treat hepatitis B in Africa

CW Spearman, MI Andersson, B Bright… - BMC Global and Public …, 2023 - Springer
There are 82 million people living with hepatitis B (PLWHB) in the World Health
Organization Africa region, where it is the main cause of liver disease. Effective vaccines …

Hepatitis B virus research in South Africa

MB Maepa, A Ely, A Kramvis, K Bloom, K Naidoo… - Viruses, 2022 - mdpi.com
Despite being vaccine-preventable, hepatitis B virus (HBV) infection remains the seventh
leading cause of mortality in the world. In South Africa (SA), over 1.9 million people are …

High prevalence of hepatitis B virus infection among people with HIV in rural and Periurban communities in Botswana

BB Phinius, M Anderson, I Gobe… - Open Forum …, 2023 - academic.oup.com
Background We aimed to determine the prevalence of hepatitis B virus (HBV) infection
among people with human immunodeficiency virus (PWH) in rural and periurban …

[HTML][HTML] Hepatitis B virus resistance to tenofovir: fact or fiction? A systematic literature review and structural analysis of drug resistance mechanisms

J Mokaya, AL McNaughton, PA Bester… - Wellcome open …, 2020 - ncbi.nlm.nih.gov
Background: Tenofovir (TFV) is a widely used treatment for chronic hepatitis B virus (HBV)
infection. There is a high genetic barrier to the selection of TFV resistance-associated …

[HTML][HTML] Evidence of tenofovir resistance in chronic hepatitis B virus (HBV) infection: An observational case series of South African adults

J Mokaya, TG Maponga, AL McNaughton… - Journal of Clinical …, 2020 - Elsevier
Introduction Tenofovir disoproxil fumarate (TDF) is widely recommended for treatment of
chronic hepatitis B virus (HBV) infection because it is safe, affordable and has a high genetic …

Hepatitis B virus (HBV) viral load, liver and renal function in adults treated with tenofovir disoproxil fumarate (TDF) vs. untreated: a retrospective longitudinal UK cohort …

T Wang, DA Smith, C Campbell, J Mokaya… - BMC infectious …, 2021 - Springer
Background Current clinical guidelines recommend treating chronic hepatitis B virus (HBV)
infection in a minority of cases, but there are relatively scarce data on evolution or …

[HTML][HTML] Barriers that prevent adults living with HBV infection from participating in clinical research: experience from South Africa

N Mofokeng, TG Maponga, M van Schalkwyk… - Journal of Virus …, 2023 - Elsevier
High profile international goals have been set for the elimination of hepatitis B virus (HBV)
infection as a public health threat by the year 2030. Developing and expanding equitable …