Obesity remains the most important risk factor for the incidence and progression of
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …

Obesity is becoming an epidemic in the United States and worldwide and increases risk for
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …

Obesity usually is accompanied by inflammation of fat tissue, with a prominent role of
visceral fat. Chronic inflammation in obese fat tissue is of a lower grade than acute immune …

The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

In the past decade, nonalcoholic fatty liver disease (NAFLD) has become a leading cause of
chronic liver disease and cirrhosis, as well as an important risk factor for hepatocellular …

Obesity-associated inflammation stems from a combination of cell-intrinsic changes of
individual immune cell subsets and the dynamic crosstalk amongst a broad array of immune …

Obesity and type 2 diabetes mellitus (T2DM) are increasing in prevalence owing to
decreases in physical activity levels and a shift to diets that include addictive and/or high …

Obesity is accompanied by inflammation in adipose tissue, impaired glucose tolerance, and
changes in adipose leukocyte populations. These studies of adipose tissue from humans …

Abstract Purpose of Review During the last decades, obesity and autoimmune disorders
have shown a parallel significant rise in industrialized countries. This review aims at …

Type 2 diabetes (T2D) is characterized by a progressive status of chronic, low-grade
inflammation (LGI) that accompanies the whole trajectory of the disease, from its inception to …