Prolactin is a hormone that is mainly secreted by lactotroph cells of the anterior pituitary
gland, and is involved in many biological processes including lactation and reproduction …

The contribution of prolactin (PRL) to the pathogenesis and progression of human breast
cancer at the cellular, transgenic, and epidemiological levels is increasingly appreciated …

▪ Abstract Prolactin (PRL) is a paradoxical hormone. Historically known as the pituitary
hormone of lactation, it has had attributed to it more than 300 separate actions, which can be …

Recent evidence suggests that prolactin may be positively associated with postmenopausal
breast cancer risk; however, little data are available in younger women. Therefore, we …

Stats (for signal transducers and activators of transcription) are a family of transcription
factors that regulate cell growth and differentiation. Their activity is latent until …

Simple Summary Prolactin receptor (PRLR) and epidermal growth factor receptor
(EGFR/ERBB) signaling pathways have a crucial role in the development of mammary …

There is a large body of literature showing that prolactin (PRL) exerts growth-promoting
activities in breast cancer, and possibly in prostate cancer and prostate hyperplasia. In …

Prolactin is important in human breast development, and substantial laboratory and in vitro
data suggest a role in mammary carcinogenesis. Therefore, we conducted a prospective …

The role of prolactin in human breast cancer has been controversial. However, it is now
apparent that human mammary epithelial cells can synthesize prolactin endogenously …

A number of epidemiologic studies of prolactin and breast cancer etiology have recently
become available. Retrospective case-control studies have suggested a modest positive or …