PCR-based detection methods for single-nucleotide polymorphism or mutation: real-time PCR and its substantial contribution toward technological refinement
K Matsuda - Advances in clinical chemistry, 2017 - Elsevier
Single-nucleotide polymorphisms (SNPs) and single-nucleotide mutations result from the
substitution of only a single base. The SNP or mutation can be relevant to disease …
substitution of only a single base. The SNP or mutation can be relevant to disease …
Immunotherapy against several tumors, such as lung cancer, including NSCLC
T Weinschenk, S Walter, J Fritsche, S Colette… - US Patent …, 2018 - Google Patents
A method of treating a patient who has non-small cell lung carcinoma (NSCLC), lung cancer,
gastric cancer, and/or glioblastoma includes administering to said patient a composition …
gastric cancer, and/or glioblastoma includes administering to said patient a composition …
Immunotherapy against several tumors, such as lung cancer, including nsclc
T Weinschenk, S Walter, J Fritsche… - US Patent App. 14 …, 2016 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
52460698&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
52460698&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Novel immunotherapy against several tumors, such as lung cancer, including nsclc
T Weinschenk, S Walter, J Fritsche, S Colette, H Singh - 2015 - Google Patents
The present invention relates to peptides, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the …
immunotherapeutic methods. In particular, the present invention relates to the …
[HTML][HTML] PNA clamping in nucleic acid amplification protocols to detect single nucleotide mutations related to cancer
MF Fouz, DH Appella - Molecules, 2020 - mdpi.com
This review describes the application of peptide nucleic acids (PNAs) as clamps that prevent
nucleic acid amplification of wild-type DNA so that DNA with mutations may be observed …
nucleic acid amplification of wild-type DNA so that DNA with mutations may be observed …
A polymorphism in the promoter region of PD-L1 serves as a binding-site for SP1 and is associated with PD-L1 overexpression and increased occurrence of gastric …
LH Tao, XR Zhou, FC Li, Q Chen, FY Meng… - Cancer Immunology …, 2017 - Springer
PD-L1 is a member of the B7 family co-inhibitory molecules and plays a critical role in tumor
immune escape. In this study, we found a polymorphism rs10815225 in the PD-L1 promoter …
immune escape. In this study, we found a polymorphism rs10815225 in the PD-L1 promoter …
[HTML][HTML] Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle
R Yang, Y Du, L Wang, Z Chen, X Liu - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Prostate cancer is a malignant tumor disease that seriously harms the lives of middle-aged
and elderly men. Weighted gene co-expression analysis can be used to construct gene co …
and elderly men. Weighted gene co-expression analysis can be used to construct gene co …
[HTML][HTML] Mechanism of glycitein in the treatment of colon cancer based on network pharmacology and molecular docking
T Xiang, W Jin - Lifestyle Genomics, 2023 - karger.com
Introduction: The prevalence of colon cancer remains high across the world. The early
diagnosis of colon cancer is challenging. Moreover, patients with colon cancer frequently …
diagnosis of colon cancer is challenging. Moreover, patients with colon cancer frequently …
[HTML][HTML] Screening and identification of potential prognostic biomarkers in adrenocortical carcinoma
WH Xu, J Wu, J Wang, FN Wan, HK Wang… - Frontiers in …, 2019 - frontiersin.org
Objective: Adrenocortical carcinoma (ACC) is a rare but aggressive malignant cancer that
has been attracting growing attention over recent decades. This study aims to integrate …
has been attracting growing attention over recent decades. This study aims to integrate …
Identification of potential hub genes associated with the pathogenesis and prognosis of hepatocellular carcinoma via integrated bioinformatics analysis
Z Meng, J Wu, X Liu, W Zhou, M Ni… - Journal of …, 2020 - journals.sagepub.com
Objective The objective was to identify potential hub genes associated with the
pathogenesis and prognosis of hepatocellular carcinoma (HCC). Methods Gene expression …
pathogenesis and prognosis of hepatocellular carcinoma (HCC). Methods Gene expression …