Esophageal cancer is a unique and complex heterogeneous malignancy, with substantial
tumor heterogeneity: at the cellular levels, tumors are composed of tumor and stromal …

Drug discovery is a generally inefficient and capital-intensive process. For
neurodegenerative diseases (NDDs), the development of novel therapeutics is particularly …

Introduction People living with HIV (PLHIV) are characterized by functional reprogramming
of innate immune cells even after long-term antiretroviral therapy (ART). In order to assess …

The cell painting (CP) assay has emerged as a potent imaging-based high-throughput
phenotypic profiling (HTPP) tool that provides comprehensive input data for in silico …

A drug Mechanism of Action (MoA) is a complex biological phenomenon that describes how
a bioactive compound produces a pharmacological effect. The complete knowledge of MoA …

Transcriptomics allows to obtain comprehensive insights into cellular programs and their
responses to perturbations. Despite a significant decrease in the costs of library production …

Background. In females, ovarian cancer is the 5th cancer-related death cause and the
deadliest gynaecological cancer. High-grade serous ovarian cancer accounts for the …