Carbon nanotubes: applications in pharmacy and medicine

H He, LA Pham-Huy, P Dramou, D Xiao… - BioMed research …, 2013 - Wiley Online Library
Carbon nanotubes (CNTs) are allotropes of carbon, made of graphite and constructed in
cylindrical tubes with nanometer in diameter and several millimeters in length. Their …

Evolving drug delivery strategies to overcome the blood brain barrier

DS Hersh, AS Wadajkar, NB Roberts… - Current …, 2016 - ingentaconnect.com
The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial …

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond

X Zhang, W Hu, J Li, L Tao, Y Wei - Toxicology Research, 2012 - academic.oup.com
Investigations of the interactions between carbon nanomaterials (CNMs) and living
organisms and their subsequent biological responses are of fundamental significance for …

Safety considerations for graphene: lessons learnt from carbon nanotubes

C Bussy, H Ali-Boucetta… - Accounts of chemical …, 2013 - ACS Publications
Many consider carbon nanomaterials the poster children of nanotechnology, attracting
immense scientific interest from many disciplines and offering tremendous potential in a …

Making carbon nanotubes biocompatible and biodegradable

A Bianco, K Kostarelos, M Prato - Chemical communications, 2011 - pubs.rsc.org
Carbon nanotubes are promising nanomaterials with great potential in the field of
nanomedicine for both therapeutic and diagnostic applications. Different approaches have …

[HTML][HTML] Functionalised carbon nanotubes: From intracellular uptake and cell-related toxicity to systemic brain delivery

PM Costa, M Bourgognon, JTW Wang… - Journal of Controlled …, 2016 - Elsevier
Carbon nanotubes (CNTs) have long been regarded as promising carriers in biomedicine.
Due to their high surface area and unique needle-like structure, CNTs are uniquely …

Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery

BR Smith, EEB Ghosn, H Rallapalli, JA Prescher… - Nature …, 2014 - nature.com
In cancer imaging, nanoparticle biodistribution is typically visualized in living subjects using
'bulk'imaging modalities such as magnetic resonance imaging, computerized tomography …

[HTML][HTML] The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo

H Kafa, JTW Wang, N Rubio, K Venner, G Anderson… - Biomaterials, 2015 - Elsevier
Carbon nanotubes (CNTs) are a novel nanocarriers with interesting physical and chemical
properties. Here we investigate the ability of amino-functionalized multi-walled carbon …

Carbon nanotubes part II: a remarkable carrier for drug and gene delivery

M Karimi, N Solati, A Ghasemi, MA Estiar… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Carbon nanotubes (CNT) have recently been studied as novel and versatile
drug and gene delivery vehicles. When CNT are suitably functionalized, they can interact …

Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes

L Lacerda, J Russier, G Pastorin, MA Herrero… - Biomaterials, 2012 - Elsevier
Understanding the mechanisms responsible for carbon nanotube (CNT) internalisation into
live cells is considered critical both from a fundamental point of view and for further …