Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

Hyperpolarized water as universal sensitivity booster in biomolecular NMR

C Hilty, D Kurzbach, L Frydman - Nature protocols, 2022 - nature.com
NMR spectroscopy is the only method to access the structural dynamics of biomolecules at
high (atomistic) resolution in their native solution state. However, this method's low …

Overhauser enhanced liquid state nuclear magnetic resonance spectroscopy in one and two dimensions

M Levien, L Yang, A van der Ham, M Reinhard… - Nature …, 2024 - nature.com
Nuclear magnetic resonance (NMR) is fundamental in the natural sciences, from chemical
analysis and structural biology, to medicine and physics. Despite its enormous …

Hyperpolarization via dissolution dynamic nuclear polarization: new technological and methodological advances

AC Pinon, A Capozzi, JH Ardenkjær-Larsen - … Resonance Materials in …, 2021 - Springer
Dissolution-DNP is a method to boost liquid-state NMR sensitivity by several orders of
magnitude. The technique consists in hyperpolarizing samples by solid-state dynamic …

High-field dynamic nuclear polarization

B Corzilius - Annual review of physical chemistry, 2020 - annualreviews.org
Dynamic nuclear polarization (DNP) is one of the most prominent methods of sensitivity
enhancement in nuclear magnetic resonance (NMR). Even though solid-state DNP under …

Room-temperature dynamic nuclear polarization enhanced NMR spectroscopy of small biological molecules in water

D Dai, X Wang, Y Liu, XL Yang, C Glaubitz… - Nature …, 2021 - nature.com
Nuclear magnetic resonance (NMR) spectroscopy is a powerful and popular technique for
probing the molecular structures, dynamics and chemical properties. However the …

Solid-like Dynamic Nuclear Polarization Observed in the Fluid Phase of Lipid Bilayers at 9.4 T

AA Kuzhelev, D Dai, V Denysenkov… - Journal of the American …, 2022 - ACS Publications
Dynamic nuclear polarization (DNP) is a powerful method to enhance NMR sensitivity. Much
progress has been achieved recently to optimize DNP performance at high magnetic fields …

Nitroxide derivatives for dynamic nuclear polarization in liquids: the role of rotational diffusion

M Levien, M Hiller, I Tkach, M Bennati… - The journal of physical …, 2020 - ACS Publications
Polarization transfer efficiency in liquid-state dynamic nuclear polarization (DNP) depends
on the interaction between polarizing agents (PAs) and target nuclei modulated by …

1H Hyperpolarization of Solutions by Overhauser Dynamic Nuclear Polarization with 13C–1H Polarization Transfer

Y Rao, A Venkatesh, P Moutzouri… - The Journal of Physical …, 2022 - ACS Publications
Dynamic nuclear polarization (DNP) is a method that can significantly increase the
sensitivity of nuclear magnetic resonance. The only effective DNP mechanism for in situ …

Cryogenic and Dissolution DNP NMR on γ-Irradiated Organic Molecules

A Giannoulis, K Butbul, R Carmieli, J Kim… - Journal of the …, 2024 - ACS Publications
Nuclear magnetic resonance (NMR) plays a central role in the elucidation of chemical
structures but is often limited by low sensitivity. Dissolution dynamic nuclear polarization …