Macrophage migration inhibitory factor (MIF): a multifaceted cytokine regulated by genetic and physiological strategies

K Sumaiya, D Langford, K Natarajaseenivasan… - Pharmacology & …, 2022 - Elsevier
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …

The pathogenic role of angiogenesis in rheumatoid arthritis

HA Elshabrawy, Z Chen, MV Volin, S Ravella… - Angiogenesis, 2015 - Springer
Angiogenesis is the formation of new capillaries from pre-existing vasculature, which plays a
critical role in the pathogenesis of several inflammatory autoimmune diseases such as …

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …

BB Aggarwal, KB Harikumar - The international journal of biochemistry & …, 2009 - Elsevier
Although safe in most cases, ancient treatments are ignored because neither their active
component nor their molecular targets are well defined. This is not the case, however, with …

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

R Wilken, MS Veena, MB Wang, ES Srivatsan - Molecular cancer, 2011 - Springer
Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant,
commonly known as turmeric. Curcumin has been used extensively in Ayurvedic medicine …

A review of therapeutic effects of curcumin

A Noorafshan… - Current pharmaceutical …, 2013 - ingentaconnect.com
There is a growing interest in herbal medicine. Scientific studies have demonstrated the
beneficial pharmacological effects of curcumin. Curcumin is a bright yellow spice, derived …

The immunobiology of MIF: function, genetics and prospects for precision medicine

I Kang, R Bucala - Nature Reviews Rheumatology, 2019 - nature.com
The role of macrophage migration inhibitory factor (MIF) in autoimmunity is underscored by
data showing that common functional polymorphisms in MIF are associated with disease …

Biological properties of curcumin-cellular and molecular mechanisms of action

B Joe, M Vijaykumar, BR Lokesh - Critical reviews in food science …, 2004 - Taylor & Francis
Curcuminoids, a group of phenolic compounds isolated from the roots of Curcuma longa
(Zingiberaceae), exhibit a variety of beneficial effects on health and on events that help in …

Natural products as a gold mine for arthritis treatment

D Khanna, G Sethi, KS Ahn, MK Pandey… - Current opinion in …, 2007 - Elsevier
Arthritis, an inflammation of the joints, is usually a chronic disease that results from
dysregulation of pro-inflammatory cytokines (eg tumour necrosis factor and interleukin-1β) …

MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis

EF Morand, M Leech, J Bernhagen - Nature reviews Drug discovery, 2006 - nature.com
Macrophage migration inhibitory factor (MIF) is well established as a key cytokine in immuno-
inflammatory diseases such as rheumatoid arthritis. Inflammation is now also recognized as …

A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis

JA Baugh, S Chitnis, SC Donnelly, J Monteiro, X Lin… - Genes & …, 2002 - nature.com
The macrophage migration inhibitory factor (MIF) is a potent pro-inflammatory cytokine and
regulates the anti-inflammator effects of glucocorticoids. An important role for MIF within the …