Macrophage migration inhibitory factor (MIF): a multifaceted cytokine regulated by genetic and physiological strategies
K Sumaiya, D Langford, K Natarajaseenivasan… - Pharmacology & …, 2022 - Elsevier
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …
The pathogenic role of angiogenesis in rheumatoid arthritis
HA Elshabrawy, Z Chen, MV Volin, S Ravella… - Angiogenesis, 2015 - Springer
Angiogenesis is the formation of new capillaries from pre-existing vasculature, which plays a
critical role in the pathogenesis of several inflammatory autoimmune diseases such as …
critical role in the pathogenesis of several inflammatory autoimmune diseases such as …
Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …
BB Aggarwal, KB Harikumar - The international journal of biochemistry & …, 2009 - Elsevier
Although safe in most cases, ancient treatments are ignored because neither their active
component nor their molecular targets are well defined. This is not the case, however, with …
component nor their molecular targets are well defined. This is not the case, however, with …
Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
R Wilken, MS Veena, MB Wang, ES Srivatsan - Molecular cancer, 2011 - Springer
Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant,
commonly known as turmeric. Curcumin has been used extensively in Ayurvedic medicine …
commonly known as turmeric. Curcumin has been used extensively in Ayurvedic medicine …
A review of therapeutic effects of curcumin
A Noorafshan… - Current pharmaceutical …, 2013 - ingentaconnect.com
There is a growing interest in herbal medicine. Scientific studies have demonstrated the
beneficial pharmacological effects of curcumin. Curcumin is a bright yellow spice, derived …
beneficial pharmacological effects of curcumin. Curcumin is a bright yellow spice, derived …
The immunobiology of MIF: function, genetics and prospects for precision medicine
I Kang, R Bucala - Nature Reviews Rheumatology, 2019 - nature.com
The role of macrophage migration inhibitory factor (MIF) in autoimmunity is underscored by
data showing that common functional polymorphisms in MIF are associated with disease …
data showing that common functional polymorphisms in MIF are associated with disease …
Biological properties of curcumin-cellular and molecular mechanisms of action
Curcuminoids, a group of phenolic compounds isolated from the roots of Curcuma longa
(Zingiberaceae), exhibit a variety of beneficial effects on health and on events that help in …
(Zingiberaceae), exhibit a variety of beneficial effects on health and on events that help in …
Natural products as a gold mine for arthritis treatment
Arthritis, an inflammation of the joints, is usually a chronic disease that results from
dysregulation of pro-inflammatory cytokines (eg tumour necrosis factor and interleukin-1β) …
dysregulation of pro-inflammatory cytokines (eg tumour necrosis factor and interleukin-1β) …
MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis
EF Morand, M Leech, J Bernhagen - Nature reviews Drug discovery, 2006 - nature.com
Macrophage migration inhibitory factor (MIF) is well established as a key cytokine in immuno-
inflammatory diseases such as rheumatoid arthritis. Inflammation is now also recognized as …
inflammatory diseases such as rheumatoid arthritis. Inflammation is now also recognized as …
A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis
JA Baugh, S Chitnis, SC Donnelly, J Monteiro, X Lin… - Genes & …, 2002 - nature.com
The macrophage migration inhibitory factor (MIF) is a potent pro-inflammatory cytokine and
regulates the anti-inflammator effects of glucocorticoids. An important role for MIF within the …
regulates the anti-inflammator effects of glucocorticoids. An important role for MIF within the …