Canine osteosarcoma (OSA) is an aggressive malignancy that frequently metastasizes to
the lung and bone. Not only has there been essentially no improvement in therapeutic …

Introduction 3. Wnt-β-catenin pathway in development of osteosarcoma 4. Wnt-β-catenin
pathway in metastatic osteosarcoma 5. Regulation of Wnt-β-catenin pathway in …

This study aimed to examine the expression of and the relationship between CD44V6,
CDH11, and β‐catenin. The expression of these cell adhesion molecules was detected in 90 …

Background In dogs with appendicular osteosarcoma (OSA), increased pretreatment serum
bone‐specific alkaline phosphatase (BALP) activity is a negative prognostic factor …

Background Osteosarcoma (OSA) represents the most common canine primary bone
tumour. Despite several pathways have been investigated so far, few molecules have been …

Osteosarcoma is an aggressive malignancy and represents the most frequent primary bone
malignancy of dogs and humans. Prognostic factors reported for osteosarcoma include …

Canine osteosarcoma (OS) is an aggressive malignancy associated with poor outcomes.
Therapeutic improvements are likely to develop from an improved understanding of …

目的研究冬凌草甲素(oridonin, ORI) 对人骨肉瘤细胞株增殖抑制和凋亡诱导作用的分子机制.
方法以结晶紫染色和Western blot 检测ORI 对143B 细胞增殖的抑制作用, Annexin V-EGFP …

In this study, we aimed to evaluate histopathologically the case of osteosarcoma detected in
an Belgian Malinois race dog. The material of the study consisted of a 8.5-year-old Belgian …