Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs

P Mohite, S Singh, A Pawar, A Sangale… - Frontiers in Drug …, 2023 - frontiersin.org
Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical
development, which is linked to their limited oral bioavailability and therapeutic efficacy. To …

Lipid-based nanocarriers for neurological disorders: a review of the state-of-the-art and therapeutic success to date

BA Witika, MS Poka, PH Demana, SK Matafwali… - Pharmaceutics, 2022 - mdpi.com
Neurodegenerative disorders including Alzheimer's, Parkinson's, and dementia are chronic
and advanced diseases that are associated with loss of neurons and other related …

Investigation of the phytochemical composition, antioxidant, antibacterial, anti-osteoarthritis, and wound healing activities of selected vegetable waste

MA Salem, OG Mohamed, EM Mosalam, AI Elberri… - Scientific reports, 2023 - nature.com
Agri-food wastes, produced following industrial food processing, are mostly discarded,
leading to environmental hazards and losing the nutritional and medicinal values associated …

A short review on chemical properties, stability and nano-technological advances for curcumin delivery

L Slika, D Patra - Expert opinion on drug delivery, 2020 - Taylor & Francis
Introduction: Curcumin is a polyphenol found in turmeric that is derived from the rhizomes of
Curcuma longa. Curcumin has received a worldwide attention due to being a major …

Comprehensive survey on nanobiomaterials for bone tissue engineering applications

P Kumar, M Saini, BS Dehiya, A Sindhu, V Kumar… - Nanomaterials, 2020 - mdpi.com
One of the most important ideas ever produced by the application of materials science to the
medical field is the notion of biomaterials. The nanostructured biomaterials play a crucial …

Antibacterial activity of antipsychotic agents, their association with lipid nanocapsules and its impact on the properties of the nanocarriers and on antibacterial activity

H Nehme, P Saulnier, AA Ramadan, V Cassisa… - PloS one, 2018 - journals.plos.org
Bacterial antibiotic resistance is an emerging public health problem worldwide; therefore,
new therapeutic strategies are needed. Many studies have described antipsychotic …

Lipid-based carriers for the delivery of local anesthetics

DR de Araujo, LNM Ribeiro… - Expert opinion on drug …, 2019 - Taylor & Francis
Introduction: There is a clinical need for pharmaceutical dosage forms devised to prolong
the acting time of local anesthetic (LA) agents or to reduce their toxicity. Encapsulation of LA …

Lipid shell lipid nanocapsules as smart generation lipid nanocarriers

N Dabholkar, T Waghule, VK Rapalli, S Gorantla… - Journal of Molecular …, 2021 - Elsevier
Lipid nanocapsules (LNCs) are lipid-based nanocarriers that have found application as drug
delivery systems, in diagnostics, and theranostics. They are biocompatible and able to …

Self-assembling lecithin-based mixed polymeric micelles for nose to brain delivery of clozapine: In-vivo assessment of drug efficacy via radiobiological evaluation

FM Elsharkawy, MM Amin… - International Journal …, 2023 - Taylor & Francis
Purpose The research objective is to design intranasal brain targeted CLZ loaded lecithin
based polymeric micelles (CLZ-LbPM) aiming to improve central systemic CLZ …

Formulation of benznidazole-lipid nanocapsules: Drug release, permeability, biocompatibility, and stability studies

EC Arrua, O Hartwig, B Loretz, X Murgia, DK Ho… - International Journal of …, 2023 - Elsevier
Benznidazole, a poorly soluble in water drug, is the first-line medication for the treatment of
Chagas disease, but long treatment periods at high dosages cause several adverse effects …