Monkeypox virus in Nigeria: infection biology, epidemiology, and evolution

E Alakunle, U Moens, G Nchinda, MI Okeke - Viruses, 2020 - mdpi.com
Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of
orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state) after 39 years of …

[HTML][HTML] Discovery and development of safe-in-man broad-spectrum antiviral agents

PI Andersen, A Ianevski, H Lysvand… - International Journal of …, 2020 - Elsevier
Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-
specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases …

Drug repurposing strategies for COVID-19

SL Senanayake - Future Drug Discovery, 2020 - Taylor & Francis
COVID-19 has now been declared a pandemic and new treatments are urgently needed as
we enter a phase beyond containment. Developing new drugs from scratch is a lengthy …

Potential antiviral options against SARS-CoV-2 infection

A Ianevski, R Yao, MH Fenstad, S Biza, E Zusinaite… - Viruses, 2020 - mdpi.com
As of June 2020, the number of people infected with severe acute respiratory coronavirus 2
(SARS-CoV-2) continues to skyrocket, with more than 6.7 million cases worldwide. Both the …

Targeting hub genes and pathways of innate immune response in COVID-19: a network biology perspective

K Prasad, F Khatoon, S Rashid, N Ali… - International journal of …, 2020 - Elsevier
The current pandemic of 2019 novel coronavirus disease (COVID-19) caused by a novel
virus strain, 2019-nCoV/SARS-CoV-2 have posed a serious threat to global public health …

Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing

J Zecha, CY Lee, FP Bayer, C Meng, V Grass… - Molecular & Cellular …, 2020 - ASBMB
As the COVID-19 pandemic continues to spread, thousands of scientists around the globe
have changed research direction to understand better how the virus works and to find out …

Medicinal plants: Treasure for antiviral drug discovery

SI Ali, WM Sheikh, MA Rather… - Phytotherapy …, 2021 - Wiley Online Library
The pandemic of viral diseases like novel coronavirus (2019‐nCoV) prompted the scientific
world to examine antiviral bioactive compounds rather than nucleic acid analogous …

Identification and tracking of antiviral drug combinations

A Ianevski, R Yao, S Biza, E Zusinaite, A Männik, G Kivi… - Viruses, 2020 - mdpi.com
Combination therapies have become a standard for the treatment for HIV and hepatitis C
virus (HCV) infections. They are advantageous over monotherapies due to better efficacy …

Brain disease network analysis to elucidate the neurological manifestations of COVID-19

K Prasad, SY AlOmar, SAM Alqahtani, MZ Malik… - Molecular …, 2021 - Springer
Although COVID-19 largely causes respiratory complications, it can also lead to various
extrapulmonary manifestations resulting in higher mortality and these comorbidities are …

Novel antiviral activities of obatoclax, emetine, niclosamide, brequinar, and homoharringtonine

PI Andersen, K Krpina, A Ianevski, N Shtaida, E Jo… - Viruses, 2019 - mdpi.com
Viruses are the major causes of acute and chronic infectious diseases in the world.
According to the World Health Organization, there is an urgent need for better control of viral …