Multi salt strategy based on curcumin pyrimidine derivatives prodrugs: Synthesis, biological activity, in vitro and in vivo imaging, and drug distribution research
G Lian, Y Liu, K Hu, M Zhou, J Feng, S Wang, C Lu… - Dyes and …, 2023 - Elsevier
Herein, a feasible strategy to enhance the water solubility of potential anti-tumor drugs was
utilized, which was to combine hydrochloric acid or sulfuric acid into its molecules. In order …
utilized, which was to combine hydrochloric acid or sulfuric acid into its molecules. In order …
Water in nigella oil microemulsion for enhanced oral bioavailability of linagliptin
RK Eid, MF Arafa, GM El Maghraby - Drug Delivery and Translational …, 2024 - Springer
Linagliptin is hydrophilic antidiabetic with poor oral bioavailability due to poor permeability
and pre-systemic metabolism. The objective was to assess w/o microemulsion for enhanced …
and pre-systemic metabolism. The objective was to assess w/o microemulsion for enhanced …
Eudragit S100 coated surfactant vesicles for boosted oral bioavailability of ticagrelor
HF Marei, MF Arafa, GM El Maghraby - Journal of Drug Delivery Science …, 2024 - Elsevier
Ticagrelor is an effective antiplatelet with only 36% oral bioavailability. Niosomes can boost
ticagrelor bioavailability. Polymer coating can prevent niosome destabilization in GIT (gastro …
ticagrelor bioavailability. Polymer coating can prevent niosome destabilization in GIT (gastro …